Gene Symbol | FAM3B |
---|---|
Entrez Gene | 54097 |
Alt Symbol | 2-21, C21orf11, C21orf76, ORF9, PANDER, PRED44 |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 3, member B |
Other Description | D21M16SJHU19e|cytokine-like protein 2-21|pancreatic derived factor|pancreatic-derived factor|protein FAM3B |
Swissprots | P58499 |
Accessions | CAM55969 EAX09608 EAX09609 EAX09610 P58499 AF375989 AAL34495 AF494379 AAM94280 AJ409094 CAC83974 AK125528 AK302095 BAH13625 AY040086 AAK74134 AY358459 AAQ88824 BC036314 BC057829 AAH57829 BF514643 BI712971 HQ257913 ADR82668 XM_011529648 XP_011527950 XM_011529649 XP_011527951 XR_937526 NM_058186 NP_478066 NM_206964 NP_996847 |
Function | Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. {ECO:0000269|PubMed:16114871}. |
Subcellular Location | Secreted. Note=Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure. |
Tissue Specificity | Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis. {ECO:0000269|PubMed:16114871}. |