Gene Symbol | FAM3B |
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Entrez Gene | 54097 |
Alt Symbol | 2-21, C21orf11, C21orf76, ORF9, PANDER, PRED44 |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 3, member B |
Other Description | D21M16SJHU19e|cytokine-like protein 2-21|pancreatic derived factor|pancreatic-derived factor|protein FAM3B |
Swissprots | P58499 |
Accessions | CAM55969 EAX09608 EAX09609 EAX09610 P58499 AF375989 AAL34495 AF494379 AAM94280 AJ409094 CAC83974 AK125528 AK302095 BAH13625 AY040086 AAK74134 AY358459 AAQ88824 BC036314 BC057829 AAH57829 BF514643 BI712971 HQ257913 ADR82668 XM_011529648 XP_011527950 XM_011529649 XP_011527951 XR_937526 NM_058186 NP_478066 NM_206964 NP_996847 |
Function | Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. {ECO:0000269|PubMed:16114871}. |
Subcellular Location | Secreted. Note=Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure. |
Tissue Specificity | Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis. {ECO:0000269|PubMed:16114871}. |
FAM3B CRISPR/Cas9 KO Plasmid (h) - sc-410589 from Santa Cruz Biotechnology
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FAM3B HDR Plasmid (h) - sc-410589-HDR from Santa Cruz Biotechnology
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FAM3B Double Nickase Plasmid (h) - sc-410589-NIC from Santa Cruz Biotechnology
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FAM3B Double Nickase Plasmid (h2) - sc-410589-NIC-2 from Santa Cruz Biotechnology
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FAM3B CRISPR Activation Plasmid (h) - sc-410589-ACT from Santa Cruz Biotechnology
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FAM3B CRISPR Activation Plasmid (h2) - sc-410589-ACT-2 from Santa Cruz Biotechnology
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FAM3B Lentiviral Activation Particles (h) - sc-410589-LAC from Santa Cruz Biotechnology
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FAM3B Lentiviral Activation Particles (h2) - sc-410589-LAC-2 from Santa Cruz Biotechnology
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FAM3B siRNA (h) - sc-91522 from Santa Cruz Biotechnology
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FAM3B shRNA Plasmid (h) - sc-91522-SH from Santa Cruz Biotechnology
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FAM3B shRNA (h) Lentiviral Particles - sc-91522-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU159841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8324 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8324 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04779 from Sigma-Aldrich
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FAM3B siRNA (Human) - CRJ0018 from Cohesion Biosciences
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FAM3B - MBS8207921 from MyBioSource
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shRNA set against Human FAM3B (NM_058186.3) - SHH291029 from Creative biogene
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shRNA set against Human FAM3B(NM_206964.1) - SHH046793 from Creative biogene
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Human FAM3B siRNA - orb270519 from Biorbyt
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FAM3B shRNA Plasmid (Human) - CHJ0018 from Cohesion Biosciences
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FAM3B miRNA 3'UTR clone - MiUTR1H-03439 from Creative biogene
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FAM3B miRNA 3'UTR clone - MiUTR1H-03440 from Creative biogene
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