| Gene Symbol |
IKBIP
|
| Entrez Gene |
121457
|
| Alt Symbol |
IKIP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
IKBKB interacting protein
|
| Other Description |
I kappa B kinase interacting protein|IKBKB-interacting protein|IKK interacting protein|IKK-interacting protein|i kappa-B kinase-interacting protein|inhibitor of nuclear factor kappa-B kinase-interacting protein
|
| Swissprots |
Q70UQ0 Q70UP9 Q96ND2 Q6ZWH4 Q86V91
|
| Accessions |
EAW97601 EAW97602 Q70UQ0 AJ539425 CAD62380 AJ539426 CAD62381 AJ539427 CAD62382 AK055613 BAB70970 AK123069 BAC85528 BC029415 AAH29415 BC051372 AAH51372 BC058933 AAH58933 BC107572 AAI07573 BM468651 HQ448064 ADQ32545 NM_153687 NP_710154 NM_201612 NP_963906 NM_201613 NP_963907
|
| Function |
Target of p53/TP53 with pro-apoptotic function. {ECO:0000269|PubMed:15389287}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:15389287}; Single-pass membrane protein {ECO:0000269|PubMed:15389287}. Note=Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization.
|
| Tissue Specificity |
Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle. {ECO:0000269|PubMed:15389287}.
|