Gene Symbol | IKBIP |
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Entrez Gene | 121457 |
Alt Symbol | IKIP |
Species | Human |
Gene Type | protein-coding |
Description | IKBKB interacting protein |
Other Description | I kappa B kinase interacting protein|IKBKB-interacting protein|IKK interacting protein|IKK-interacting protein|i kappa-B kinase-interacting protein|inhibitor of nuclear factor kappa-B kinase-interacting protein |
Swissprots | Q70UQ0 Q70UP9 Q96ND2 Q6ZWH4 Q86V91 |
Accessions | EAW97601 EAW97602 Q70UQ0 AJ539425 CAD62380 AJ539426 CAD62381 AJ539427 CAD62382 AK055613 BAB70970 AK123069 BAC85528 BC029415 AAH29415 BC051372 AAH51372 BC058933 AAH58933 BC107572 AAI07573 BM468651 HQ448064 ADQ32545 NM_153687 NP_710154 NM_201612 NP_963906 NM_201613 NP_963907 |
Function | Target of p53/TP53 with pro-apoptotic function. {ECO:0000269|PubMed:15389287}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15389287}; Single-pass membrane protein {ECO:0000269|PubMed:15389287}. Note=Isoform 4 deletion of the hydrophobic, or transmembrane region between AA 45-63 results in uniform distribution throughout the cell, suggesting that this region is responsible for endoplasmic reticulum localization. |
Tissue Specificity | Expressed in vein endothelial cells. Isoform 4 is expressed in lung, kidney, spleen, thymus and skeletal muscle. {ECO:0000269|PubMed:15389287}. |
IKIP CRISPR/Cas9 KO Plasmid (h) - sc-409021 from Santa Cruz Biotechnology
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IKIP HDR Plasmid (h) - sc-409021-HDR from Santa Cruz Biotechnology
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IKIP Double Nickase Plasmid (h) - sc-409021-NIC from Santa Cruz Biotechnology
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IKIP Double Nickase Plasmid (h2) - sc-409021-NIC-2 from Santa Cruz Biotechnology
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IKIP CRISPR Activation Plasmid (h) - sc-409021-ACT from Santa Cruz Biotechnology
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IKIP CRISPR Activation Plasmid (h2) - sc-409021-ACT-2 from Santa Cruz Biotechnology
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IKIP Lentiviral Activation Particles (h) - sc-409021-LAC from Santa Cruz Biotechnology
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IKIP Lentiviral Activation Particles (h2) - sc-409021-LAC-2 from Santa Cruz Biotechnology
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IKIP siRNA (h) - sc-96217 from Santa Cruz Biotechnology
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IKIP shRNA Plasmid (h) - sc-96217-SH from Santa Cruz Biotechnology
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IKIP shRNA (h) Lentiviral Particles - sc-96217-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU099091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10551 from Sigma-Aldrich
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IKBIP siRNA (Human) - CRJ4674 from Cohesion Biosciences
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IKBIP - MBS8238848 from MyBioSource
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shRNA set against Human IKBIP (NM_201612.2) - SHH317977 from Creative biogene
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Human IKBIP siRNA - orb275175 from Biorbyt
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IKBIP shRNA Plasmid (Human) - CHJ4674 from Cohesion Biosciences
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IKBIP miRNA 3'UTR clone - MiUTR3H-10851 from Creative biogene
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IKBIP miRNA 3'UTR clone - MiUTR3H-10852 from Creative biogene
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IKBIP miRNA 3'UTR clone - MiUTR3H-10853 from Creative biogene
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