| Gene Symbol |
SH3GL3
|
| Entrez Gene |
6457
|
| Alt Symbol |
CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SH3-domain GRB2-like 3
|
| Other Description |
SH3 domain protein 2C|SH3 domain-containing GRB2-like protein 3|endophilin-3|endophilin-A3
|
| Swissprots |
O43554 Q99963 O43553
|
| Accessions |
EAW62419 EAW62420 EAW62421 EAW62422 EAW62423 Q99963 AF036269 AAC04765 AF036270 AAC04766 AF036271 AAC04767 AK307442 AK309086 AL109775 CAB52431 BC035598 BC042864 AAH42864 BP228213 X99664 CAA67978 XM_011521888 XP_011520190 XM_011521889 XP_011520191 XM_011521890 XP_011520192 XM_011521891 XP_011520193 XM_011521892 XP_011520194 XR_931878 XR_931879 XR_931880 XR_931881 XR_931882 NM_001301108 NP_001288037 NM_001301109 NP_001288038 NM_003027 NP_003018 NR_125370
|
| Function |
Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Early endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Brain and testis.
|
| Top Pathways |
Endocytosis
|
![Western Blot: SH3GL3 Overexpression Lysate (Adult Normal) [NBP2-08046] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SH3GL3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/24460_SH3GL3%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08046-img0001.jpg)