Gene Symbol | SH3GL3 |
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Entrez Gene | 6457 |
Alt Symbol | CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13 |
Species | Human |
Gene Type | protein-coding |
Description | SH3-domain GRB2-like 3 |
Other Description | SH3 domain protein 2C|SH3 domain-containing GRB2-like protein 3|endophilin-3|endophilin-A3 |
Swissprots | O43554 Q99963 O43553 |
Accessions | EAW62419 EAW62420 EAW62421 EAW62422 EAW62423 Q99963 AF036269 AAC04765 AF036270 AAC04766 AF036271 AAC04767 AK307442 AK309086 AL109775 CAB52431 BC035598 BC042864 AAH42864 BP228213 X99664 CAA67978 XM_011521888 XP_011520190 XM_011521889 XP_011520191 XM_011521890 XP_011520192 XM_011521891 XP_011520193 XM_011521892 XP_011520194 XR_931878 XR_931879 XR_931880 XR_931881 XR_931882 NM_001301108 NP_001288037 NM_001301109 NP_001288038 NM_003027 NP_003018 NR_125370 |
Function | Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Early endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons (By similarity). {ECO:0000250}. |
Tissue Specificity | Brain and testis. |
Top Pathways | Endocytosis |
Endophilin III CRISPR/Cas9 KO Plasmid (h) - sc-403821 from Santa Cruz Biotechnology
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Endophilin III HDR Plasmid (h) - sc-403821-HDR from Santa Cruz Biotechnology
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Endophilin III Double Nickase Plasmid (h) - sc-403821-NIC from Santa Cruz Biotechnology
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Endophilin III Double Nickase Plasmid (h2) - sc-403821-NIC-2 from Santa Cruz Biotechnology
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Endophilin III CRISPR Activation Plasmid (h) - sc-403821-ACT from Santa Cruz Biotechnology
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Endophilin III CRISPR Activation Plasmid (h2) - sc-403821-ACT-2 from Santa Cruz Biotechnology
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Endophilin III Lentiviral Activation Particles (h) - sc-403821-LAC from Santa Cruz Biotechnology
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Endophilin III Lentiviral Activation Particles (h2) - sc-403821-LAC-2 from Santa Cruz Biotechnology
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Endophilin III siRNA (h) - sc-35308 from Santa Cruz Biotechnology
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Endophilin III shRNA Plasmid (h) - sc-35308-SH from Santa Cruz Biotechnology
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Endophilin III shRNA (h) Lentiviral Particles - sc-35308-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU093881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19272 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19272 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03995 from Sigma-Aldrich
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SH3GL3 siRNA (Human) - CRH4367 from Cohesion Biosciences
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SH3GL3 - MBS8220327 from MyBioSource
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shRNA set against Human SH3GL3 (NM_003027.3) - SHH406764 from Creative biogene
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Human SH3GL3 siRNA - orb264869 from Biorbyt
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SH3GL3 shRNA Plasmid (Human) - CHH4367 from Cohesion Biosciences
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SH3GL3 miRNA 3'UTR clone - MiUTR3H-05892 from Creative biogene
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