Gene Symbol | FAR2 |
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Entrez Gene | 55711 |
Alt Symbol | MLSTD1, SDR10E2 |
Species | Human |
Gene Type | protein-coding |
Description | fatty acyl CoA reductase 2 |
Other Description | fatty acyl-CoA reductase 2|male sterility domain-containing protein 1|short chain dehydrogenase/reductase family 10E, member 2 |
Swissprots | Q96K12 Q9NVW8 Q9H0D5 F8VV73 |
Accessions | EAW96586 EAW96587 Q96K12 AK001324 BAA91625 AK001927 BAA91983 AK027756 BAB55347 AK129857 AK314670 BAG37227 AL136843 CAB66777 BC018460 BC022267 AAH22267 CB217408 DA068892 DA848036 XM_011520747 XP_011519049 XM_011520748 XP_011519050 NM_001271783 NP_001258712 NM_001271784 NP_001258713 NM_018099 NP_060569 |
Function | Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18:1 and C18:2 but low activity can be observed with C10-C14 substrates. {ECO:0000269|PubMed:15220348}. |
Subcellular Location | Peroxisome membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Peroxisome in cells expressing low levels of the protein. Peroxisome and endoplasmic reticulum in cells expressing high levels of the protein. |
Top Pathways | Peroxisome |
FAR2 CRISPR/Cas9 KO Plasmid (h) - sc-410023 from Santa Cruz Biotechnology
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FAR2 HDR Plasmid (h) - sc-410023-HDR from Santa Cruz Biotechnology
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FAR2 Double Nickase Plasmid (h) - sc-410023-NIC from Santa Cruz Biotechnology
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FAR2 Double Nickase Plasmid (h2) - sc-410023-NIC-2 from Santa Cruz Biotechnology
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FAR2 CRISPR Activation Plasmid (h) - sc-410023-ACT from Santa Cruz Biotechnology
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FAR2 CRISPR Activation Plasmid (h2) - sc-410023-ACT-2 from Santa Cruz Biotechnology
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FAR2 Lentiviral Activation Particles (h) - sc-410023-LAC from Santa Cruz Biotechnology
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FAR2 Lentiviral Activation Particles (h2) - sc-410023-LAC-2 from Santa Cruz Biotechnology
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FAR2 siRNA (h) - sc-96223 from Santa Cruz Biotechnology
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FAR2 shRNA Plasmid (h) - sc-96223-SH from Santa Cruz Biotechnology
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FAR2 shRNA (h) Lentiviral Particles - sc-96223-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU106311 from Sigma-Aldrich
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MISSION® esiRNA - EHU118701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8481 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02310 from Sigma-Aldrich
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FAR2 siRNA (Human) - CRJ0853 from Cohesion Biosciences
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FAR2 - MBS8230186 from MyBioSource
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shRNA set against Human FAR2 (NM_018099.3) - SHH292401 from Creative biogene
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shRNA set against Human MLSTD1(NM_018099.3) - SHH192575 from Creative biogene
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Human FAR2 siRNA - orb271354 from Biorbyt
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FAR2 shRNA Plasmid (Human) - CHJ0853 from Cohesion Biosciences
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FAR2 miRNA 3'UTR clone - MiUTR1H-06335 from Creative biogene
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