| Gene Symbol |
MBOAT1
|
| Entrez Gene |
154141
|
| Alt Symbol |
1, LPEAT1, LPLAT, LPLAT 1, LPSAT, OACT1, dJ434O11.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
membrane bound O-acyltransferase domain containing 1
|
| Other Description |
1-acylglycerophosphoserine O-acyltransferase|O-acyltransferase (membrane bound) domain containing 1|O-acyltransferase domain-containing protein 1|lyso-PS acyltransferase|lysophosphatidylethanolamine acyltransferase 1|lysophosphatidylserine acyltransferase|lysophospholipid acyltransferase 1|membrane-bound O-acyltransferase domain-containing protein 1
|
| Swissprots |
B4E3J4 Q8N9R5 Q6ZNC8 B4DL59 Q86XC2 A9EDQ5
|
| Accessions |
Q6ZNC8 AB305043 BAF93899 AK093994 BAC04264 AK131269 BAD18447 AK296857 BAG59421 AK304748 BAG65506 BC045695 BC150650 AAI50651 BC150652 AAI50653 BC156593 AAI56594 BM978819 XM_006714999 XP_006715062 XM_006715000 XP_006715063 XM_011514313 XP_011512615 XR_926070 XR_926071 NM_001080480 NP_001073949 NR_073465
|
| Function |
Acyltransferase which mediates the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L- serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3- phospho-L-serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. {ECO:0000269|PubMed:18772128}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Expressed in neutrophils. {ECO:0000269|PubMed:18772128}.
|
| Top Pathways |
Glycerolipid metabolism, Glycerophospholipid metabolism
|