ZFP36

Gene Symbol	ZFP36
Entrez Gene	7538
Alt Symbol	G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36
Species	Human
Gene Type	protein-coding
Description	ZFP36 ring finger protein
Other Description	G0/G1 switch regulatory protein 24|growth factor-inducible nuclear protein NUP475|tristetraprolin|tristetraproline|zinc finger protein 36 homolog|zinc finger protein 36, C3H type, homolog|zinc finger protein, C3H type, 36 homolog
Swissprots	P26651 B2RA54
Accessions	AAC37600 AAV28731 CBX47646 EAW56885 EAW56886 P26651 AJ227917 AK314042 BAG36751 BC009693 AAH09693 BM055332 EU446714 ABZ92243 EU832179 ACE87529 EU832272 ACE86842 M63625 AAA61240 M92843 AAA58489 NM_003407 NP_003398
Function	mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post- transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). {ECO:0000269|PubMed:15014438, ECO:0000269|PubMed:23644599}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15014438}. Cytoplasm {ECO:0000269|PubMed:15014438}. Note=Localizes to stress granules upon energy starvation. phosphorylation by MAPKAPK2 promotes exclusion from stress granules.
Top Pathways	HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Tristetraprolin full length protein - ab112374 from Abcam Category Protein Source Wheat germ Species Human

Human Tristetraprolin peptide - ab111664 from Abcam Category Peptide Species Human

Tristetraprolin peptide - ab106207 from Abcam Category Peptide

ZFP36 / Tristetraprolin Antibody Blocking Peptide - LS-E12181 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZFP36 / Tristetraprolin Antibody Blocking Peptide - LS-E12182 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZFP36 / Tristetraprolin Antibody Blocking Peptide - LS-E13759 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TTP Protein - H00007538-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ZFP36-Antibody-Center-Blocking-Peptide - BP8952c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Tristetraproline (TTP) - H00007538-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Tristetraproline (TTP) - H00007538-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ZFP36 fusion protein - Ag3461 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ZFP36 - ZFP36-31616TH from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human ZFP36, GST-tagged - ZFP36-3801H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Tristetraprolin(ZFP36) - CSB-YP026448HU CSB-EP026448HU CSB-BP026448HU CSB-MP026448HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TTP Blocking Peptide - 3551BP-50 from Biovision Category Peptide Prices $95.00 Sizes 50 μg

TTP, Peptide - MBS843888 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

ZFP36 Peptide, Human - M34GP17792H from Creative Peptides Category Peptide Source Synthetic. Species Human

ZFP36 fusion protein - Ag28473 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Recombinant Human ZFP36 Protein, GST/His-tagged - ZFP36-313H from Creative Biomart Category Protein Source E. coli Species Human

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