ZFP36

Gene Symbol ZFP36
Entrez Gene 7538
Alt Symbol G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36
Species Human
Gene Type protein-coding
Description ZFP36 ring finger protein
Other Description G0/G1 switch regulatory protein 24|growth factor-inducible nuclear protein NUP475|tristetraprolin|tristetraproline|zinc finger protein 36 homolog|zinc finger protein 36, C3H type, homolog|zinc finger protein, C3H type, 36 homolog
Swissprots P26651 B2RA54
Accessions AAC37600 AAV28731 CBX47646 EAW56885 EAW56886 P26651 AJ227917 AK314042 BAG36751 BC009693 AAH09693 BM055332 EU446714 ABZ92243 EU832179 ACE87529 EU832272 ACE86842 M63625 AAA61240 M92843 AAA58489 NM_003407 NP_003398
Function mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post- transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). {ECO:0000269|PubMed:15014438, ECO:0000269|PubMed:23644599}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15014438}. Cytoplasm {ECO:0000269|PubMed:15014438}. Note=Localizes to stress granules upon energy starvation. phosphorylation by MAPKAPK2 promotes exclusion from stress granules.
Top Pathways HTLV-I infection

TTP CRISPR/Cas9 KO Plasmid (h) - sc-400722 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTP HDR Plasmid (h) - sc-400722-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTP Double Nickase Plasmid (h) - sc-400722-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTP Double Nickase Plasmid (h2) - sc-400722-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTP CRISPR Activation Plasmid (h) - sc-400722-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTP CRISPR Activation Plasmid (h2) - sc-400722-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTP Lentiviral Activation Particles (h) - sc-400722-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTP Lentiviral Activation Particles (h2) - sc-400722-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTP siRNA (h) - sc-36760 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TTP shRNA Plasmid (h) - sc-36760-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TTP shRNA (h) Lentiviral Particles - sc-36760-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TTP RNAi - H00007538-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU007031 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23181 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23181 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05890 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05890

ZFP36 siRNA (Human) - CRH5150 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZFP36 - MBS8236349 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZFP36 (NM_003407.3) - SHH450888 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZFP36 siRNA - orb265652 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZFP36 shRNA Plasmid (Human) - CHH5150 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZFP36 miRNA 3'UTR clone - MiUTR3H-02289 from Creative biogene

Species Reactivities Human
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