| Gene Symbol |
OTOP1
|
| Entrez Gene |
133060
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
otopetrin 1
|
| Other Description |
otopetrin-1
|
| Swissprots |
Q7RTM1 A1L476
|
| Accessions |
DAA00902 EAW82445 EAW82446 Q7RTM1 BC130430 AAI30431 BC130432 AAI30433 BK000653 DAA00901 NM_177998 NP_819056
|
| Function |
Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein. Secreted, extracellular space. Note=Detected in the gelatinous membrane overlying the inner ear macular epithelium. {ECO:0000250}.
|