LYPLA1

Gene Symbol LYPLA1
Entrez Gene 10434
Alt Symbol APT-1, APT1, LPL-I, LPL1, hAPT1
Species Human
Gene Type protein-coding
Description lysophospholipase I
Other Description acyl-protein thioesterase 1|lysoPLA I|lysophospholipid-specific lysophospholipase
Swissprots O43202 Q9UQF9 O75608
Accessions EAW86742 EAW86743 EAW86744 EAW86745 EAW86746 O75608 AA307642 AA827237 AF035293 AAB88180 AF052112 AF077198 AAD26993 AF077199 AAD26994 AF081281 AAC31610 AF291053 AAG10063 AK289400 BAF82089 AK298206 BAG60476 AK307277 AK313739 BAG36480 BC008652 AAH08652 BC010397 AAH10397 CR457103 CAG33384 DA817192 DA881616 DA883059 DQ891527 ABM82453 DQ894717 ABM85643 XM_005251127 XP_005251184 NM_001279356 NP_001266285 NM_001279357 NP_001266286 NM_001279358 NP_001266287 NM_001279359 NP_001266288 NM_001279360 NP_001266289 NM_006330 NP_006321
Function Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity. {ECO:0000269|PubMed:20418879, ECO:0000269|PubMed:22399288}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Choline metabolism in cancer, Glycerophospholipid metabolism

LYPLA1 CRISPR/Cas9 KO Plasmid (h) - sc-411470 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA1 HDR Plasmid (h) - sc-411470-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA1 Double Nickase Plasmid (h) - sc-411470-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA1 Double Nickase Plasmid (h2) - sc-411470-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA1 CRISPR Activation Plasmid (h) - sc-411470-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA1 CRISPR Activation Plasmid (h2) - sc-411470-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA1 Lentiviral Activation Particles (h) - sc-411470-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA1 Lentiviral Activation Particles (h2) - sc-411470-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYPLA1 siRNA (h) - sc-77637 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LYPLA1 shRNA Plasmid (h) - sc-77637-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LYPLA1 shRNA (h) Lentiviral Particles - sc-77637-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LYPLA1 RNAi - H00010434-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU114771 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN12861 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12861 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10223 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10223

LYPLA1 siRNA (Human) - CRH7076 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LYPLA1(NM_006330.2) - SHH168545 from Creative biogene

Category siRNA
Species Reactivities Human

Human LYPLA1 siRNA - orb267578 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LYPLA1 shRNA Plasmid (Human) - CHH7076 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LYPLA1 miRNA 3'UTR clone - MiUTR1H-05976 from Creative biogene

Species Reactivities Human
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