| Gene Symbol | TTC37 |
|---|---|
| Entrez Gene | 9652 |
| Alt Symbol | KIAA0372, Ski3, THES |
| Species | Human |
| Gene Type | protein-coding |
| Description | tetratricopeptide repeat domain 37 |
| Other Description | SKI3 homolog|TPR repeat protein 37|tetratricopeptide repeat protein 37|thespin|tricho-hepatic-enteric syndrome protein |
| Swissprots | O15077 Q6PGP7 Q6PJI3 |
| Accessions | EAW96037 EAW96038 Q6PGP7 AB002370 BAA20827 AK307531 BC009767 BC015163 AAH15163 BC030966 BC056893 AAH56893 XR_948312 NM_014639 NP_055454 |
| Function | Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16024656}. Nucleus {ECO:0000269|PubMed:16024656}. |
| Tissue Specificity | Widely expressed with the highest levels observed in vascular tissues, lymph node, pituitary, lung and intestine. Not expressed in the liver. {ECO:0000269|PubMed:21120949}. |
| Top Pathways | RNA degradation |