| Gene Symbol |
TTC37
|
| Entrez Gene |
9652
|
| Alt Symbol |
KIAA0372, Ski3, THES
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tetratricopeptide repeat domain 37
|
| Other Description |
SKI3 homolog|TPR repeat protein 37|tetratricopeptide repeat protein 37|thespin|tricho-hepatic-enteric syndrome protein
|
| Swissprots |
O15077 Q6PGP7 Q6PJI3
|
| Accessions |
EAW96037 EAW96038 Q6PGP7 AB002370 BAA20827 AK307531 BC009767 BC015163 AAH15163 BC030966 BC056893 AAH56893 XR_948312 NM_014639 NP_055454
|
| Function |
Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C).
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16024656}. Nucleus {ECO:0000269|PubMed:16024656}.
|
| Tissue Specificity |
Widely expressed with the highest levels observed in vascular tissues, lymph node, pituitary, lung and intestine. Not expressed in the liver. {ECO:0000269|PubMed:21120949}.
|
| Top Pathways |
RNA degradation
|