| Gene Symbol | SCARA5 |
|---|---|
| Entrez Gene | 286133 |
| Alt Symbol | NET33, Tesr |
| Species | Human |
| Gene Type | protein-coding |
| Description | scavenger receptor class A, member 5 |
| Other Description | scavenger receptor class A member 5|scavenger receptor class A, member 5 (putative)|scavenger receptor hlg|testis expressed scavenger receptor |
| Swissprots | Q6ZMJ2 Q6UXZ1 Q8N4Z7 Q7Z4A1 |
| Accessions | EAW63532 EAW63533 EAW63534 Q6ZMJ2 AA934589 AK172746 BAD18733 AK301006 BAG62624 AY337579 AAQ17470 AY358150 AAQ88517 BC033153 AAH33153 BQ944057 DA991818 DA993754 NM_173833 NP_776194 |
| Function | Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) (By similarity). {ECO:0000250}. |
| Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |