Gene Symbol | SCARA5 |
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Entrez Gene | 286133 |
Alt Symbol | NET33, Tesr |
Species | Human |
Gene Type | protein-coding |
Description | scavenger receptor class A, member 5 |
Other Description | scavenger receptor class A member 5|scavenger receptor class A, member 5 (putative)|scavenger receptor hlg|testis expressed scavenger receptor |
Swissprots | Q6ZMJ2 Q6UXZ1 Q8N4Z7 Q7Z4A1 |
Accessions | EAW63532 EAW63533 EAW63534 Q6ZMJ2 AA934589 AK172746 BAD18733 AK301006 BAG62624 AY337579 AAQ17470 AY358150 AAQ88517 BC033153 AAH33153 BQ944057 DA991818 DA993754 NM_173833 NP_776194 |
Function | Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
SCARA5 CRISPR/Cas9 KO Plasmid (h) - sc-407005 from Santa Cruz Biotechnology
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SCARA5 HDR Plasmid (h) - sc-407005-HDR from Santa Cruz Biotechnology
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SCARA5 Double Nickase Plasmid (h) - sc-407005-NIC from Santa Cruz Biotechnology
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SCARA5 Double Nickase Plasmid (h2) - sc-407005-NIC-2 from Santa Cruz Biotechnology
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SCARA5 CRISPR Activation Plasmid (h) - sc-407005-ACT from Santa Cruz Biotechnology
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SCARA5 CRISPR Activation Plasmid (h2) - sc-407005-ACT-2 from Santa Cruz Biotechnology
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SCARA5 Lentiviral Activation Particles (h) - sc-407005-LAC from Santa Cruz Biotechnology
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SCARA5 Lentiviral Activation Particles (h2) - sc-407005-LAC-2 from Santa Cruz Biotechnology
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SCARA5 siRNA (h) - sc-77423 from Santa Cruz Biotechnology
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SCARA5 shRNA Plasmid (h) - sc-77423-SH from Santa Cruz Biotechnology
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SCARA5 shRNA (h) Lentiviral Particles - sc-77423-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN18892 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18892 from Sigma-Aldrich
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SCARA5 siRNA (Human) - CRJ7151 from Cohesion Biosciences
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SCARA5 RNAi - H00286133-R02 from Novus Biologicals
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SCARA5 - MBS8236171 from MyBioSource
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SCARA5 CRISPR/Cas9 KO Plasmid (h2) - sc-407005-KO-2 from Santa Cruz Biotechnology
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SCARA5 HDR Plasmid (h2) - sc-407005-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human SCARA5 (NM_173833.5) - SHH402396 from Creative biogene
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Human SCARA5 siRNA - orb277652 from Biorbyt
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SCARA5 shRNA Plasmid (Human) - CHJ7151 from Cohesion Biosciences
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SCARA5 miRNA 3'UTR clone - MiUTR4H-TG07819 from Creative biogene
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