Gene Symbol | CFC1 |
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Entrez Gene | 55997 |
Alt Symbol | CFC1B, CRYPTIC, DTGA2, HTX2 |
Species | Human |
Gene Type | protein-coding |
Description | cripto, FRL-1, cryptic family 1 |
Other Description | cryptic family protein 1|cryptic protein|heterotaxy 2 (autosomal dominant) |
Swissprots | P0CG37 |
Accessions | AAG42475 CCA65395 P0CG37 AF312769 AAG30294 AK290094 BAF82783 AK315326 BAG37727 BC069508 AAH69508 BC074825 AAH74825 BC074826 AAH74826 BC110080 AAI10081 BC146897 AAI46898 BG654700 BI793242 BM310214 BM509218 CA777249 CA941621 CA948246 DQ786275 XM_011511486 XP_011509788 NM_001270420 NP_001257349 NM_001270421 NP_001257350 NM_032545 NP_115934 |
Function | NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation. {ECO:0000269|PubMed:11062482}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:18930707}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:18930707}. Secreted {ECO:0000269|PubMed:18930707}. Note=Does not exhibit a typical GPI-signal sequence. The C-ter hydrophilic extension of the GPI- signal sequence reduces the efficiency of processing and could lead to the production of an secreted unprocessed form. This extension is found only in primates. |
Cryptic CRISPR/Cas9 KO Plasmid (h) - sc-416247 from Santa Cruz Biotechnology
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Cryptic HDR Plasmid (h) - sc-416247-HDR from Santa Cruz Biotechnology
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Cryptic Double Nickase Plasmid (h) - sc-416247-NIC from Santa Cruz Biotechnology
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Cryptic Double Nickase Plasmid (h2) - sc-416247-NIC-2 from Santa Cruz Biotechnology
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Cryptic CRISPR Activation Plasmid (h) - sc-416247-ACT from Santa Cruz Biotechnology
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Cryptic CRISPR Activation Plasmid (h2) - sc-416247-ACT-2 from Santa Cruz Biotechnology
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Cryptic Lentiviral Activation Particles (h) - sc-416247-LAC from Santa Cruz Biotechnology
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Cryptic Lentiviral Activation Particles (h2) - sc-416247-LAC-2 from Santa Cruz Biotechnology
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Cryptic siRNA (h) - sc-60453 from Santa Cruz Biotechnology
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Cryptic shRNA Plasmid (h) - sc-60453-SH from Santa Cruz Biotechnology
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Cryptic shRNA (h) Lentiviral Particles - sc-60453-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU149021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5995 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5995 from Sigma-Aldrich
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CFC1 siRNA (Human) - CRJ1035 from Cohesion Biosciences
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CFC1 - MBS8222579 from MyBioSource
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shRNA set against Human CFC1 (NM_032545.3) - SHH262377 from Creative biogene
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Human CFC1 siRNA - orb271536 from Biorbyt
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CFC1 shRNA Plasmid (Human) - CHJ1035 from Cohesion Biosciences
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CFC1 miRNA 3'UTR clone - MiUTR4H-TG02035 from Creative biogene
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