Gene Symbol |
NECAB3
|
Entrez Gene |
63941
|
Alt Symbol |
APBA2BP, EFCBP3, NIP1, STIP3, SYTIP2, XB51, dJ63M2.4, dJ63M2.5
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
N-terminal EF-hand calcium binding protein 3
|
Other Description |
EF-hand calcium binding protein 3|N-terminal EF-hand calcium-binding protein 3|Nek2-interacting protein 1|X11L-binding protein 51|amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein|amyloid beta A4 protein-binding family A member 2-binding protein|neuronal calcium-binding protein 3|neuronal calcium-binding protein NECAB3|synaptotagmin interacting protein 2|synaptotagmin interacting protein STIP3
|
Swissprots |
Q5JWF7 Q9H8G8 Q9HCQ9 Q96P71 A8K780 E1P5N2 Q5JWF5 Q5JWF6 Q9H433 Q9HBW7 Q86VV1
|
Accessions |
EAW76301 EAW76302 EAW76303 EAW76304 EAW76305 EAW76306 EAW76307 EAW76308 Q96P71 AB039947 BAB16413 AF193759 AAG28415 AF409141 AAL01118 AK023706 BAB14649 AK124388 AK291895 BAF84584 AK309285 AL519842 BC023270 BC047673 AAH47673 BQ212085 BQ431858 CD580591 XM_005260510 XP_005260567 XM_011528987 XP_011527289 XM_011528988 XP_011527290 XM_011528989 XP_011527291 XM_011528990 XP_011527292 XM_011528991 XP_011527293 XM_011528992 XP_011527294 XR_244145 NM_031231 NP_112508 NM_031232 NP_112509
|
Function |
Inhibits the interaction of APBA2 with beta-amyloid precursor protein (APP), and hence allows formation of beta- amyloid. {ECO:0000269|PubMed:10833507}.
|
Subcellular Location |
Golgi apparatus {ECO:0000269|PubMed:10833507, ECO:0000269|PubMed:14697346}.
|
Tissue Specificity |
Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas. {ECO:0000269|PubMed:10833507, ECO:0000269|PubMed:12044471}.
|