Gene Symbol | NECAB3 |
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Entrez Gene | 63941 |
Alt Symbol | APBA2BP, EFCBP3, NIP1, STIP3, SYTIP2, XB51, dJ63M2.4, dJ63M2.5 |
Species | Human |
Gene Type | protein-coding |
Description | N-terminal EF-hand calcium binding protein 3 |
Other Description | EF-hand calcium binding protein 3|N-terminal EF-hand calcium-binding protein 3|Nek2-interacting protein 1|X11L-binding protein 51|amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein|amyloid beta A4 protein-binding family A member 2-binding protein|neuronal calcium-binding protein 3|neuronal calcium-binding protein NECAB3|synaptotagmin interacting protein 2|synaptotagmin interacting protein STIP3 |
Swissprots | Q5JWF7 Q9H8G8 Q9HCQ9 Q96P71 A8K780 E1P5N2 Q5JWF5 Q5JWF6 Q9H433 Q9HBW7 Q86VV1 |
Accessions | EAW76301 EAW76302 EAW76303 EAW76304 EAW76305 EAW76306 EAW76307 EAW76308 Q96P71 AB039947 BAB16413 AF193759 AAG28415 AF409141 AAL01118 AK023706 BAB14649 AK124388 AK291895 BAF84584 AK309285 AL519842 BC023270 BC047673 AAH47673 BQ212085 BQ431858 CD580591 XM_005260510 XP_005260567 XM_011528987 XP_011527289 XM_011528988 XP_011527290 XM_011528989 XP_011527291 XM_011528990 XP_011527292 XM_011528991 XP_011527293 XM_011528992 XP_011527294 XR_244145 NM_031231 NP_112508 NM_031232 NP_112509 |
Function | Inhibits the interaction of APBA2 with beta-amyloid precursor protein (APP), and hence allows formation of beta- amyloid. {ECO:0000269|PubMed:10833507}. |
Subcellular Location | Golgi apparatus {ECO:0000269|PubMed:10833507, ECO:0000269|PubMed:14697346}. |
Tissue Specificity | Strongly expressed in heart and skeletal muscle, moderately in brain and pancreas. {ECO:0000269|PubMed:10833507, ECO:0000269|PubMed:12044471}. |
APBA2BP CRISPR/Cas9 KO Plasmid (h) - sc-410086 from Santa Cruz Biotechnology
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APBA2BP HDR Plasmid (h) - sc-410086-HDR from Santa Cruz Biotechnology
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APBA2BP Double Nickase Plasmid (h) - sc-410086-NIC from Santa Cruz Biotechnology
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APBA2BP Double Nickase Plasmid (h2) - sc-410086-NIC-2 from Santa Cruz Biotechnology
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APBA2BP CRISPR Activation Plasmid (h) - sc-410086-ACT from Santa Cruz Biotechnology
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APBA2BP CRISPR Activation Plasmid (h2) - sc-410086-ACT-2 from Santa Cruz Biotechnology
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APBA2BP Lentiviral Activation Particles (h) - sc-410086-LAC from Santa Cruz Biotechnology
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APBA2BP Lentiviral Activation Particles (h2) - sc-410086-LAC-2 from Santa Cruz Biotechnology
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APBA2BP siRNA (h) - sc-72511 from Santa Cruz Biotechnology
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APBA2BP shRNA Plasmid (h) - sc-72511-SH from Santa Cruz Biotechnology
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APBA2BP shRNA (h) Lentiviral Particles - sc-72511-V from Santa Cruz Biotechnology
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NECAB3 RNAi - H00063941-R02 from Novus Biologicals
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NECAB3 RNAi - H00063941-R01 from Novus Biologicals
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MISSION® esiRNA - EHU098491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15182 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15182 from Sigma-Aldrich
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NECAB3 siRNA (Human) - CRJ1876 from Cohesion Biosciences
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shRNA set against Human NECAB3 (NM_031232.3) - SHH351016 from Creative biogene
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NECAB3 shRNA Plasmid (Human) - CHJ1876 from Cohesion Biosciences
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NECAB3 miRNA 3'UTR clone - MiUTR1H-00452 from Creative biogene
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NECAB3 miRNA 3'UTR clone - MiUTR1H-00453 from Creative biogene
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