| Gene Symbol |
Fscn2
|
| Entrez Gene |
238021
|
| Alt Symbol |
A930022G03, C630046B20Rik, ahl8
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
|
| Other Description |
fascin-2|retinal fascin
|
| Swissprots |
Q32M02 Q8BWU0
|
| Accessions |
EDL34739 Q32M02 AK044556 AK050002 BAC34026 AK078674 BB279997 BC109356 AAI09357 BC109357 AAI09358 XM_006533259 XP_006533322 NM_172802 NP_766390
|
| Function |
Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Important for maintaining functional hair-cell bundless in the inner ear. May stiffen the longer stereocilia of hair-cell bundles in the inner ear enabling better force transmission to tip links. {ECO:0000269|PubMed:20660251}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20660251}. Cell projection, stereocilium {ECO:0000269|PubMed:20660251}. Note=Found mostly in longer hair- cell stereocilia and, in all stereocilia, present in gradient with the highest concentration at stereocilia tips.
|
| Tissue Specificity |
Expressed in the inner ear.
|