GCFC2

Gene Symbol GCFC2
Entrez Gene 6936
Alt Symbol C2orf3, DNABF, GCF, TCF9
Species Human
Gene Type protein-coding
Description GC-rich sequence DNA-binding factor 2
Other Description GC binding factor|GC bindng factor|TCF-9|transcription factor 9 (binds GC-rich sequences)
Swissprots P16383 A4UHQ8 Q6P2F2 Q53TY0 O95032 A4UHQ9
Accessions AAY14973 EAW99586 EAW99587 EAW99588 EAW99589 P16383 AB026911 BAA85386 AK097564 BAG53487 BC000853 AAH00853 BC064559 AAH64559 BG506463 BM749635 BQ880304 BU189326 BU568226 BU623860 BU628451 BU852546 BU853933 BX109258 DB259435 DB455842 EF158467 ABO84856 EF158468 ABO84857 EF158469 ABO84858 XM_005264520 XP_005264577 XM_011533074 XP_011531376 XM_011533075 XP_011531377 XR_426995 NM_001201334 NP_001188263 NM_001201335 NP_001188264 NM_003203 NP_003194
Function Factor that represses transcription. It binds to the GC- rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons. {ECO:0000269|PubMed:24304693}.
Subcellular Location Nucleus, nucleoplasm {ECO:0000269|PubMed:24304693}. Nucleus, nucleolus {ECO:0000269|PubMed:24304693}.
Tissue Specificity Widely expressed in tissues and cell lines.

GCF (H-87) - sc-366876 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GCF (H-87): sc-366876. Western blot analysis of GCF expression in HeLa (A), A-431 (B), Jurkat (C), U-937 (D) and K-562 (E) nuclear extracts.

GCF (K-13) - sc-133418 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
GCF (K-13): sc-133418. Western blot analysis of GCF expression in HeLa (A), ES-2 (B) and PC-3 (C) whole cell lysates.

GCF (T-14) - sc-133419 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
GCF (T-14): sc-133419. Western blot analysis of GCF expression in HeLa (A), ES-2 (B), PC-3 (C) and MIA PaCa-2 (D) whole cell lysates.

Anti-C2orf3 antibody - ab83407 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-C2orf3 antibody (ab83407) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal lung lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-C2orf3 antibody - ab69069 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-C2orf3 antibody (ab69069) at 1/500 dilutionLane 1 : C2orf3 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat anti-mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

Anti-GCFC2 Antibody (aa175-225) - LS-C288685 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GCFC2 Antibody (aa731-781) - LS-C288690 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GCFC2 Antibody (aa134-183) - LS-C291981 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GCFC2 Antibody - LS-C306647 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GCFC2 Antibody (aa193-238) - LS-C313975 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GCFC2 Antibody (N-Terminus) - LS-C346006 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of GCFC2 Antibody with human 293T Whole Cell lysate.

Anti-GCFC2 Antibody (aa180-229) - LS-C102747 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
C2orf3 antibody LS-C102747 Western blot of Fetal Lung lysate.

GCFC2 Antibody - NBP1-05984 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GCFC2 Antibody [NBP1-05984] - Whole cell lysate from HeLa and mouse NIH3T3 cells. GCF was also immunoprecipitated by rabbit anti-GCF antibody NBP1-05985.

GCFC2 Antibody - H00006936-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: GCFC2 Antibody [H00006936-B01] - analysis of C2orf3 expression in transfected 293T cell line by C2orf3 MaxPab polyclonal antibody (B01). Lane 1: C2orf3 transfected lysate (23.76 KDa). Lane 2: Non-transfected lysate.

GCFC2 Antibody - H00006936-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: GCFC2 Antibody [H00006936-B01P] - Analysis of C2orf3 expression in transfected 293T cell line by C2orf3 polyclonal antibody. Lane 1: C2orf3 transfected lysate(23.76 KDa). Lane 2: Non-transfected lysate.

GCFC2 Antibody - NBP1-68520 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GCFC2 Antibody [NBP1-68520] - Analysis of extracts from RAW264.7 cells, using GCFC2 Antibody. The lane on the right is treated with the synthesized peptide.

GCFC2 Antibody - NBP1-05985 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GCFC2 Antibody [NBP1-05985] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-GCF antibody used for IP at 3 mcg/mg lysate. GCF was also immunoprecipitated by rabbit anti-GCF antibody NBP1-05984, which recognizes an upstream epitope

C2orf3 Polyclonal Antibody - bs-15014R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TCF9 Polyclonal Antibody - bs-9812R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C2orf3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15014R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C2orf3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15014R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C2orf3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15014R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C2orf3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15014R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C2orf3 Polyclonal Antibody, Cy3 Conjugated - bs-15014R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C2orf3 Polyclonal Antibody, Cy5 Conjugated - bs-15014R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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