| Gene Symbol |
GCFC2
|
| Entrez Gene |
6936
|
| Alt Symbol |
C2orf3, DNABF, GCF, TCF9
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GC-rich sequence DNA-binding factor 2
|
| Other Description |
GC binding factor|GC bindng factor|TCF-9|transcription factor 9 (binds GC-rich sequences)
|
| Swissprots |
P16383 A4UHQ8 Q6P2F2 Q53TY0 O95032 A4UHQ9
|
| Accessions |
AAY14973 EAW99586 EAW99587 EAW99588 EAW99589 P16383 AB026911 BAA85386 AK097564 BAG53487 BC000853 AAH00853 BC064559 AAH64559 BG506463 BM749635 BQ880304 BU189326 BU568226 BU623860 BU628451 BU852546 BU853933 BX109258 DB259435 DB455842 EF158467 ABO84856 EF158468 ABO84857 EF158469 ABO84858 XM_005264520 XP_005264577 XM_011533074 XP_011531376 XM_011533075 XP_011531377 XR_426995 NM_001201334 NP_001188263 NM_001201335 NP_001188264 NM_003203 NP_003194
|
| Function |
Factor that represses transcription. It binds to the GC- rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons. {ECO:0000269|PubMed:24304693}.
|
| Subcellular Location |
Nucleus, nucleoplasm {ECO:0000269|PubMed:24304693}. Nucleus, nucleolus {ECO:0000269|PubMed:24304693}.
|
| Tissue Specificity |
Widely expressed in tissues and cell lines.
|