Grin1

Gene Symbol	Grin1
Entrez Gene	24408
Alt Symbol	GluN1, NMDAR1, NR1
Species	Rat
Gene Type	protein-coding
Description	glutamate receptor, ionotropic, N-methyl D-aspartate 1
Other Description	N-methyl-D-aspartate glutamate receptor\|N-methyl-D-aspartate receptor subunit NR1\|NMD-R1\|NMDA R1 receptor C1 cassette\|glutamate [NMDA] receptor subunit zeta-1\|glutamate receptor ionotropic, NMDA 1\|neurotransmitter receptor
Swissprots	P35439 Q62646
Accessions	EDL93606 EDL93607 EDL93608 EDL93609 EDL93610 EDL93611 EDL93612 EDL93613 P35439 AY090615 AAM09025 FM039130 S39221 AAB22435 U08261 AAB50926 U08262 AAB50927 U08263 AAB50928 U08264 AAB50929 U08265 AAB50930 U08266 AAB50931 U08267 AAB50932 U08268 AAB50933 U11418 AAA19659 X63255 CAA44914 X65227 CAA46335 XM_006233555 XP_006233617 XM_006233556 XP_006233618 NM_001270602 NP_001257531 NM_001270603 NP_001257532 NM_001270605 NP_001257534 NM_001270606 NP_001257535 NM_001270608 NP_001257537 NM_001270610 NP_001257539 NM_001287423 NP_001274352 NM_017010 NP_058706
Function	NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. {ECO:0000269\|PubMed:15996549}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. {ECO:0000250}.
Top Pathways	Amphetamine addiction, Circadian entrainment, cAMP signaling pathway, Alcoholism, Rap1 signaling pathway

Anti-NMDAR1 C1 antibody - ab6484 from Abcam

Prices	$359.00
Sizes	25 µg
Host	Rabbit
Clonality	Polyclonal

NMDAR1 Antibody (R1JHL) - NB300-118 from Novus Biologicals

Prices	$329.00
Sizes	15 µg
Host	Mouse
Clonality	Monoclonal
Clone	R1JHL

Western Blot: NMDAR1 Antibody (R1JHL) [NB300-118]

NMDAR1 Antibody - NB100-74473 from Novus Biologicals

Prices	$329.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: NMDAR1 Antibody [NB100-74473] - Rat brain tissue.

NMDAR2C Splice Variant Antibody - NB300-116 from Novus Biologicals

Prices	$279.00
Sizes	25 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: NMDAR2C Splice Variant Antibody [NB300-116] - Western blot of 10 ug of HEK 293 cells expression. (Lane A) NR1-subunit that does not contain the NR1 Insert (Mock). (Lane B) NR1-subunit containing only the C2 Insert. (Lane C) NR1-subunit containing the C1 and C2 in sert. (Lane D) NR1-subunit containing the C1/C2' and N1/C2' insert.

NMDAR2C Prime Splice Variant Antibody - NB300-117 from Novus Biologicals

Prices	$299.00
Sizes	25 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: NMDAR2C Prime Splice Variant Antibody [NB300-117] - Western blot of 10 ug of HEK 293 cells expression. (Lane A) NR1-subunit that does not contain the NR1 Insert (Mock). (Lane B) NR1-subunit containing only the C2 Insert. (Lane C) NR1-subunit containing the C1 and C2 insert. (Lane D) NR1-subunit containing the C11/C2' and N1/C2' insert.

NMDAR1 Antibody - NB100-41105 from Novus Biologicals

Prices	$299.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Western Blot: NMDAR1 Antibody [NB100-41105] - (2ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Monoclonal Anti-Glun1-Nr1 - Rpe antibody produced in mouse - SAB5200562 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

<B>Immunoblotting</B><BR/>Monoclonal Anti-GluN1-NR1: Western Blot analysis of Rat brain membrane lysate using NMDAR1 NMDA receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Glun1-Nr1 - Atto 680 antibody produced in mouse - SAB5200553 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Streptavidin antibody produced in mouse - SAB5200563 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Alkaline Phosphatase antibody produced in mouse - SAB5200555 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Fitc antibody produced in mouse - SAB5200558 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Atto 565 antibody produced in mouse - SAB5200549 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Percp antibody produced in mouse - SAB5200561 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert N1) antibody produced in rabbit - G0541 from Sigma-Aldrich

Prices	$466.00
Sizes	25 µg
Host	Rabbit
Clonality	Polyclonal

Monoclonal Anti-Glun1-Nr1 - Apc antibody produced in mouse - SAB5200556 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Atto 488 antibody produced in mouse - SAB5200548 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Atto 655 antibody produced in mouse - SAB5200552 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Pe/Atto 594 antibody produced in mouse - SAB5200560 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Atto 700 antibody produced in mouse - SAB5200554 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Biotin antibody produced in mouse - SAB5200557 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Atto 633 antibody produced in mouse - SAB5200551 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 - Hrp antibody produced in mouse - SAB5200559 from Sigma-Aldrich

Prices	$395.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Monoclonal Anti-Glun1-Nr1 antibody produced in mouse - SAB5200546 from Sigma-Aldrich

Prices	$335.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

Anti-NMDA Receptor, NR1 Subunit (OAPC00043) - OAPC00043 from Aviva Systems Biology

Prices	$349.00
Sizes	15 µg
Host	Mouse
Clonality	Monoclonal
Clone	R1JHL

GluN1-NR1 Antibody (OASE00258) - OASE00258 from Aviva Systems Biology

Prices	$350.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	S308-48

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