| Gene Symbol |
SPRY3
|
| Entrez Gene |
10251
|
| Alt Symbol |
spry-3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sprouty homolog 3 (Drosophila)
|
| Other Description |
antagonist of FGF signaling|protein sprouty homolog 3
|
| Swissprots |
A8K0H8 O43610
|
| Accessions |
CAB96768 EAW55876 O43610 AF041038 AAC39567 AK094610 AK125483 BAC86177 AK289543 BAF82232 AK311508 BC069609 AAH69609 BC074972 AAH74972 BC074973 AAH74973 BU164699 DA102958 HQ448462 ADQ32942 XM_011531098 XP_011529400 XM_011531099 XP_011529401 XM_011531100 XP_011529402 XM_011531101 XP_011529403 NM_001304990 NP_001291919 NM_005840 NP_005831
|
| Function |
May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
|
| Subcellular Location |
Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
|
| Tissue Specificity |
Widely expressed; particularly in the fetal tissues.
|