Gene Symbol | SPRY3 |
---|---|
Entrez Gene | 10251 |
Alt Symbol | spry-3 |
Species | Human |
Gene Type | protein-coding |
Description | sprouty homolog 3 (Drosophila) |
Other Description | antagonist of FGF signaling|protein sprouty homolog 3 |
Swissprots | A8K0H8 O43610 |
Accessions | CAB96768 EAW55876 O43610 AF041038 AAC39567 AK094610 AK125483 BAC86177 AK289543 BAF82232 AK311508 BC069609 AAH69609 BC074972 AAH74972 BC074973 AAH74973 BU164699 DA102958 HQ448462 ADQ32942 XM_011531098 XP_011529400 XM_011531099 XP_011529401 XM_011531100 XP_011529402 XM_011531101 XP_011529403 NM_001304990 NP_001291919 NM_005840 NP_005831 |
Function | May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. |
Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor). |
Tissue Specificity | Widely expressed; particularly in the fetal tissues. |