AQP4

Gene Symbol AQP4
Entrez Gene 361
Alt Symbol HMIWC2, MIWC
Species Human
Gene Type protein-coding
Description aquaporin 4
Other Description WCH4|aquaporin 4 isoform delta4|aquaporin type4|aquaporin-4|mercurial-insensitive water channel
Swissprots P78564 P55087
Accessions AAG17964 EAX01228 EAX01229 P55087 AB128929 BAD22823 AB209156 BAD92393 AK026728 AK222684 BAD96404 AK295069 BAG58116 AL119338 AL138136 AV725241 BC022286 AAH22286 BC030745 BC045780 BI596912 BI667387 BI917845 BQ638704 CD105892 CK001094 D63412 BAA09715 HQ447648 ADQ32133 HQ901095 ADZ13511 KF055862 AGX27825 N50070 R35726 U34845 AAC50284 U63622 AAB26957 U63623 AAB26958 XM_011525942 XP_011524244 NM_001650 NP_001641 NM_004028 NP_004019
Function Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Brain - muscle >> heart, kidney, lung, and trachea.
Top Pathways Vasopressin-regulated water reabsorption, Bile secretion

AQP4 (F-7) - sc-390636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AQP4 (F-7): sc-390636. Western blot analysis of expression in human stomach (A) and human skeletal muscle (B) tissue extracts.

AQP4 (B-5) - sc-390488 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AQP4 (B-5): sc-390488. Western blot analysis of AQP4 expression in human stomach (A) and human skeletal muscle (B) tissue extracts.

AQP4 (C-19) - sc-9888 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AQP4 (C-19): sc-9888. Western blot analysis of AQP4 expression in rat kidney (A) and mouse kidney (B) tissue extracts.

AQP4 (4/18) - sc-32739 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AQP4 (4/18): sc-32739. Immunofluorescence staining of rat cerebral cortex. Kindly provided by Nagy G. at University of Pecs, Hungary.

AQP4 (H-19) - sc-9887 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AQP4 (H-19): sc-9887. Western blot analysis of AQP4 expression in rat kidney (A) and mouse kidney (B) tissue extracts.

AQP4 (H-80) - sc-20812 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AQP4 (H-80): sc-20812. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing membrane staining of alveolar cells and macrophages. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Anti-Aquaporin 4 antibody - ab81355 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab81355 stained SKNSH cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab81355, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Aquaporin 4 antibody - ab156924 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Aquaporin 4 antibody (ab156924) at 1 µg/mlLane 1 : Brain (Rat) Tissue LysateLane 2 : Brain (Mouse) Tissue LysateLane 3 : Rat Cerebellum Neuronal cell lysateLane 4 : Cerebellum Rat Tissue LysateLane 5 : Spinal Cord (Mouse) Tissue LysateLane 6 : Spinal Cord (Rat) Tissue LysateLane 7 : Kidney (Rat) Tissue LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Aquaporin 4 antibody - ab125049 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Aquaporin 4 antibody (ab125049) at 1/2000 dilutionLane 1 : Rat kidney lysateLane 2 : Rat kidney lysate

Anti-Aquaporin 4 antibody - ab85904 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-Aquaporin 4 antibody [3D2] - ab11026 from Abcam

Prices $387.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3D2

Anti-Aquaporin 4 antibody [EPR7040] - ab128906 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7040
ab128906 at 1/100 dilution, staining Aquaporin 4 in paraffin-embedded Human brain tissue by Immunohistochemistry.

Anti-AQP4 / Aquaporin 4 Antibody (aa280-296) - LS-C3805 from LifeSpan Bioscience

Prices $590.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AQP4 / Aquaporin 4 Antibody (aa280-296) - LS-C3808 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-AQP4 / Aquaporin 4 Antibody (C-Terminus) - LS-C126879 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AQP4 / Aquaporin 4 Antibody (aa301-318) - LS-C69212 from LifeSpan Bioscience

Prices $545.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-AQP4 / Aquaporin 4 Antibody (C-Terminus, Magnetic beads) - LS-C172005 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AQP4 / Aquaporin 4 Antibody (aa273-291, Atto 655) - LS-C229817 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AQP4 / Aquaporin 4 Antibody (aa301-318, clone 3D2) - LS-C202597 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D2

Anti-AQP4 / Aquaporin 4 Antibody (C-Terminus, Sepharose) - LS-C172006 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AQP4 / Aquaporin 4 Antibody (Internal, clone EPR7040) - LS-C152388 from LifeSpan Bioscience

Prices $470.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7040
IHC of paraffin-embedded human brain tissue using anti-Aquaporin 4 antibody.

Anti-AQP4 / Aquaporin 4 Antibody (aa273-291, Atto 390) - LS-C229818 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AQP4 / Aquaporin 4 Antibody (aa273-291, Atto 680) - LS-C229819 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AQP4 / Aquaporin 4 Antibody (aa273-291, AP) - LS-C229821 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AQP4 / Aquaporin 4 Antibody (aa273-291, APC) - LS-C229822 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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