Gene Symbol | PURA |
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Entrez Gene | 5813 |
Alt Symbol | MRD31, PUR-ALPHA, PUR1, PURALPHA |
Species | Human |
Gene Type | protein-coding |
Description | purine-rich element binding protein A |
Other Description | purine-rich single-stranded DNA-binding protein alpha|transcriptional activator protein Pur-alpha |
Swissprots | Q00577 |
Accessions | EAW62076 Q00577 BC036087 AAH36087 BC110574 AAI10575 BC110594 AAI10595 BT019388 AAV38195 CK819077 M96684 AAA60229 X91648 NM_005859 NP_005850 |
Function | This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination. |
Subcellular Location | Nucleus. |
Purα CRISPR/Cas9 KO Plasmid (h) - sc-403760 from Santa Cruz Biotechnology
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Purα HDR Plasmid (h) - sc-403760-HDR from Santa Cruz Biotechnology
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Purα Double Nickase Plasmid (h) - sc-403760-NIC from Santa Cruz Biotechnology
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Purα Double Nickase Plasmid (h2) - sc-403760-NIC-2 from Santa Cruz Biotechnology
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Purα CRISPR Activation Plasmid (h) - sc-403760-ACT from Santa Cruz Biotechnology
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Purα CRISPR Activation Plasmid (h2) - sc-403760-ACT-2 from Santa Cruz Biotechnology
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Purα Lentiviral Activation Particles (h) - sc-403760-LAC from Santa Cruz Biotechnology
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Purα Lentiviral Activation Particles (h2) - sc-403760-LAC-2 from Santa Cruz Biotechnology
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Purα siRNA (h) - sc-91623 from Santa Cruz Biotechnology
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Purα shRNA Plasmid (h) - sc-91623-SH from Santa Cruz Biotechnology
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Purα shRNA (h) Lentiviral Particles - sc-91623-V from Santa Cruz Biotechnology
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PURA RNAi - H00005813-R01 from Novus Biologicals
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MISSION® esiRNA - EHU057641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17737 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17737 from Sigma-Aldrich
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PURA siRNA (Human) - CRH3929 from Cohesion Biosciences
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shRNA set against Human PURA (NM_005859.4) - SHH387044 from Creative biogene
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PURA shRNA Plasmid (Human) - CHH3929 from Cohesion Biosciences
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PURA miRNA 3'UTR clone - MiUTR3H-03397 from Creative biogene
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