RXRB

Gene Symbol RXRB
Entrez Gene 6257
Alt Symbol DAUDI6, H-2RIIBP, NR2B2, RCoR-1
Species Human
Gene Type protein-coding
Description retinoid X receptor, beta
Other Description MHC class I promoter binding protein|nuclear receptor subfamily 2 group B member 2|retinoic acid receptor RXR-beta
Swissprots Q5JP92 Q5STQ1 P28702 Q59G65 P28703
Accessions AAC18599 AAD13794 CAA20239 CAI95622 EAX03679 P28702 AB209244 BAD92481 AK225842 AK295759 BAH12180 AK300402 BAH13278 AK301096 BAH13409 AK302125 BAH13631 AW473828 BC001167 AAH01167 BE704198 BM982876 BT007280 AAP35944 DC425042 HQ692844 ADZ17355 HQ709179 ADZ17386 M84820 AAA60293 X63522 CAA45087 X63523 X65463 CAA46456 X66424 XM_005249278 XP_005249335 XM_005249279 XP_005249336 XM_005272854 XP_005272911 XM_005272855 XP_005272912 XM_005275007 XP_005275064 XM_005275008 XP_005275065 XM_005275149 XP_005275206 XM_005275150 XP_005275207 XM_005275276 XP_005275333 XM_005275277 XP_005275334 XM_005275438 XP_005275495 XM_005275439 XP_005275496 XM_011514796 XP_011513098 XM_011547269 XP_011545571 XM_011547672 XP_011545974 XM_011547899 XP_011546201 XM_011548071 XP_011546373 XM_011548260 XP_011546562 XR_926297 XR_952211 XR_952639 XR_952836 XR_952946 XR_953009 NM_001270401 NP_001257330 NM_001291989 NP_001278918 NM_021976 NP_068811
Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity). Specifically binds 9-cis retinoic acid (9C-RA). {ECO:0000250}.
Subcellular Location Nucleus.
Tissue Specificity Expressed in a variety of tumor cell lines. {ECO:0000269|PubMed:8381386}.
Top Pathways Small cell lung cancer, Non-small cell lung cancer, Adipocytokine signaling pathway, PPAR signaling pathway, Thyroid cancer

RXRβ Antibody - 8715 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using RXRβ Antibody.

RARβ 2 (H-55) - sc-14028 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RARβ<sub>2</sub> (H-55): sc-14028. Western blot analysis of human recombinant RARβ<sub>2</sub> fusion protein.

RXR (C-20) - sc-831 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RXR (C-20): sc-831. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tumor showing nuclear localization.

RXRβ (11-13) - sc-742 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RXRβ (11-13): sc-742. Western blot analysis of RXRβ expression in K-562 (A) and SK-BR-3 (B) nuclear extracts.

RXRβ (13-17) - sc-741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

RXRβ 1 (L-20) - sc-556 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RXRβ<sub>1</sub> (L-20): sc-556. Western blot analysis of RXRβ<sub>1</sub> expression in A-431 (A), Y79 (B), MM-142 (C) and NIH/3T3 (D) nuclear extracts.

RXRβ 2 (MOK13-17) - sc-56869 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RXRβ<sub>2</sub> (MOK13-17): sc-56869. Western blot analysis of RXRβ<sub>2</sub> expression in A-431 (A), NIH/3T3 (B) and SK-BR-3 (C) nuclear extracts.

RXRβ 2 (S-20) - sc-554 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Retinoid X Receptor beta antibody - ab15032 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Retinoid X Receptor beta antibody - ab103027 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Retinoid X Receptor beta antibody (ab103027) at 1/100 dilution + MDA-MB231 cell lysate at 35 µg

Anti-Retinoid X Receptor beta antibody - ab96824 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Retinoid X Receptor beta antibody (ab96824) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-Retinoid X Receptor beta antibody [MOK13-17] - ab2815 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MOK13-17
Overlay histogram showing Ramos cells stained with ab2815 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab2815, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive signal in Ramos cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-RXRB Antibody (clone MOK13-17) - LS-C26244 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MOK13-17

Anti-RXRB Antibody (Hinge Peptide) - LS-C93428 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-RXRB Antibody (aa262-292, APC) - LS-C285186 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXRB Antibody (aa262-292, AP) - LS-C285187 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXRB Antibody (aa262-292, FITC) - LS-C285189 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXRB Antibody (aa262-292, Azide-free, HRP) - LS-C285190 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXRB Antibody (aa70-83) - LS-C20208 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Staining (1 ug/ml) of A431 lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Anti-RXRB Antibody (aa262-292, Biotin) - LS-C285188 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXRB Antibody (aa28-77) - LS-C80747 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Brain cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

Anti-RXRB Antibody (aa262-292, PE) - LS-C285191 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RXRB Antibody (aa151-200) - LS-C80748 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-RXRB Antibody (aa451-500) - LS-C80266 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-RXRB Antibody - LS-C109381 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: A431. 7.5% SDS PAGE. RXRB antibody diluted at 1:1000.
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