| Gene Symbol |
CAPZA1
|
| Entrez Gene |
829
|
| Alt Symbol |
CAPPA1, CAPZ, CAZ1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
capping protein (actin filament) muscle Z-line, alpha 1
|
| Other Description |
Cap Z|F-actin-capping protein subunit alpha-1|capZ alpha-1
|
| Swissprots |
Q6FHD5 Q53FQ6 P52907
|
| Accessions |
EAW56525 EAW56526 EAW56527 P52907 AJ227918 AK223226 BAD96946 AK289654 BAF82343 BC000144 AAH00144 BC034391 BT019364 AAV38171 BX648738 CR407657 CAG28585 CR541819 CAG46618 DB233456 DQ890754 ABM81680 DQ893919 ABM84845 U56637 AAC00533 XM_011542225 XP_011540527 NM_006135 NP_006126
|
| Function |
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}.
|