Gene Symbol | CAPZA1 |
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Entrez Gene | 829 |
Alt Symbol | CAPPA1, CAPZ, CAZ1 |
Species | Human |
Gene Type | protein-coding |
Description | capping protein (actin filament) muscle Z-line, alpha 1 |
Other Description | Cap Z|F-actin-capping protein subunit alpha-1|capZ alpha-1 |
Swissprots | Q6FHD5 Q53FQ6 P52907 |
Accessions | EAW56525 EAW56526 EAW56527 P52907 AJ227918 AK223226 BAD96946 AK289654 BAF82343 BC000144 AAH00144 BC034391 BT019364 AAV38171 BX648738 CR407657 CAG28585 CR541819 CAG46618 DB233456 DQ890754 ABM81680 DQ893919 ABM84845 U56637 AAC00533 XM_011542225 XP_011540527 NM_006135 NP_006126 |
Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. |
CapZ-α1 CRISPR/Cas9 KO Plasmid (h) - sc-405348 from Santa Cruz Biotechnology
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CapZ-α1 HDR Plasmid (h) - sc-405348-HDR from Santa Cruz Biotechnology
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CapZ-α1 Double Nickase Plasmid (h) - sc-405348-NIC from Santa Cruz Biotechnology
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CapZ-α1 Double Nickase Plasmid (h2) - sc-405348-NIC-2 from Santa Cruz Biotechnology
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CapZ-α1 CRISPR Activation Plasmid (h) - sc-405348-ACT from Santa Cruz Biotechnology
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CapZ-α1 CRISPR Activation Plasmid (h2) - sc-405348-ACT-2 from Santa Cruz Biotechnology
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CapZ-α1 Lentiviral Activation Particles (h) - sc-405348-LAC from Santa Cruz Biotechnology
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CapZ-α1 Lentiviral Activation Particles (h2) - sc-405348-LAC-2 from Santa Cruz Biotechnology
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CapZ-α1 siRNA (h) - sc-72787 from Santa Cruz Biotechnology
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CapZ-α1 shRNA Plasmid (h) - sc-72787-SH from Santa Cruz Biotechnology
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CapZ-α1 shRNA (h) Lentiviral Particles - sc-72787-V from Santa Cruz Biotechnology
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CAPZA1 RNAi - H00000829-R01 from Novus Biologicals
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MISSION® esiRNA - EHU107831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5357 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5357 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09381 from Sigma-Aldrich
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CAPZA1 siRNA (Human) - CRH0583 from Cohesion Biosciences
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CAPZA1 - MBS8217052 from MyBioSource
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CapZ-α1 CRISPR/Cas9 KO Plasmid (h2) - sc-405348-KO-2 from Santa Cruz Biotechnology
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CapZ-α1 HDR Plasmid (h2) - sc-405348-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CAPZA1 (NM_006135.2) - SHH254497 from Creative biogene
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shRNA set against Human CAPZA1(NM_006135.2) - SHG133687 from Creative biogene
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Human CAPZA1 siRNA - orb261085 from Biorbyt
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CAPZA1 shRNA Plasmid (Human) - CHH0583 from Cohesion Biosciences
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CAPZA1 miRNA 3'UTR clone - MiUTR1H-01667 from Creative biogene
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