| Gene Symbol |
TPP2
|
| Entrez Gene |
7174
|
| Alt Symbol |
TPP-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tripeptidyl peptidase II
|
| Other Description |
TPP-II|tripeptidyl aminopeptidase|tripeptidyl-peptidase 2|tripeptidyl-peptidase II
|
| Swissprots |
Q5VZU8 P29144
|
| Accessions |
EAX09059 P29144 AK097678 AK127549 AK304313 BAH14156 AU132468 BC024905 BC039905 AAH39905 BI492495 M55169 AAA63263 M73047 AAA36760 XM_005254070 XP_005254127 XM_005254071 XP_005254128 XM_005254072 XP_005254129 XM_005254073 XP_005254130 XM_011521108 XP_011519410 XR_243046 NM_003291 NP_003282
|
| Function |
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19747897}. Nucleus {ECO:0000269|PubMed:19747897}. Note=Translocates to the nucleus in responce to gamma-irradiation.
|
![Western Blot: Tripeptidyl peptidase II Overexpression Lysate (Adult Normal) [NBL1-17224] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Tripeptidyl peptidase II.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6472_Tripeptidyl%2520peptidase%2520II%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17224-img0002.jpg)