Gene Symbol | TPP2 |
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Entrez Gene | 7174 |
Alt Symbol | TPP-2 |
Species | Human |
Gene Type | protein-coding |
Description | tripeptidyl peptidase II |
Other Description | TPP-II|tripeptidyl aminopeptidase|tripeptidyl-peptidase 2|tripeptidyl-peptidase II |
Swissprots | Q5VZU8 P29144 |
Accessions | EAX09059 P29144 AK097678 AK127549 AK304313 BAH14156 AU132468 BC024905 BC039905 AAH39905 BI492495 M55169 AAA63263 M73047 AAA36760 XM_005254070 XP_005254127 XM_005254071 XP_005254128 XM_005254072 XP_005254129 XM_005254073 XP_005254130 XM_011521108 XP_011519410 XR_243046 NM_003291 NP_003282 |
Function | Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:19747897}. Nucleus {ECO:0000269|PubMed:19747897}. Note=Translocates to the nucleus in responce to gamma-irradiation. |
TPPII CRISPR/Cas9 KO Plasmid (h) - sc-403717 from Santa Cruz Biotechnology
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TPPII HDR Plasmid (h) - sc-403717-HDR from Santa Cruz Biotechnology
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TPPII Double Nickase Plasmid (h) - sc-403717-NIC from Santa Cruz Biotechnology
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TPPII Double Nickase Plasmid (h2) - sc-403717-NIC-2 from Santa Cruz Biotechnology
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TPPII CRISPR Activation Plasmid (h) - sc-403717-ACT from Santa Cruz Biotechnology
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TPPII CRISPR Activation Plasmid (h2) - sc-403717-ACT-2 from Santa Cruz Biotechnology
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TPPII Lentiviral Activation Particles (h) - sc-403717-LAC from Santa Cruz Biotechnology
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TPPII Lentiviral Activation Particles (h2) - sc-403717-LAC-2 from Santa Cruz Biotechnology
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TPPII siRNA (h) - sc-106629 from Santa Cruz Biotechnology
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TPPII shRNA Plasmid (h) - sc-106629-SH from Santa Cruz Biotechnology
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TPPII shRNA (h) Lentiviral Particles - sc-106629-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21874 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21874 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07598 from Sigma-Aldrich
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TPP2 siRNA (Human) - CRH4925 from Cohesion Biosciences
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TPP2 - MBS8208139 from MyBioSource
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shRNA set against Human Tpp2 (NM_003291.2) - SHH433396 from Creative biogene
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TPP2 shRNA Plasmid (Human) - CHH4925 from Cohesion Biosciences
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TPP2 miRNA 3'UTR clone - MiUTR3H-02288 from Creative biogene
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