UCHL5

Gene Symbol UCHL5
Entrez Gene 51377
Alt Symbol CGI-70, INO80R, UCH-L5, UCH37
Species Human
Gene Type protein-coding
Description ubiquitin carboxyl-terminal hydrolase L5
Other Description INO80 complex subunit R|ubiquitin C-terminal hydrolase UCH37|ubiquitin carboxyl-terminal esterase L5|ubiquitin carboxyl-terminal hydrolase isozyme L5|ubiquitin thioesterase L5
Swissprots Q5LJA6 Q8TBS4 Q9Y5K5 Q9UQN2 Q9H1W5 Q96BJ9 Q9P0I3 Q5LJA7
Accessions EAW91233 EAW91234 EAW91235 EAW91236 EAW91237 EAW91238 Q9Y5K5 AF147717 AAD31528 AF151828 AAD34065 AF157320 AAF67486 AK024751 AK123655 AK225794 AK296487 BAG59125 AK301381 BAG62921 AK314445 BAG37054 AK316064 BAH14435 BC015381 BC015521 AAH15521 BC025369 AAH25369 BI548319 BT006790 AAP35436 DA255130 JF432659 ADZ15876 XM_005245244 XP_005245301 XM_005245245 XP_005245302 XM_005245246 XP_005245303 XM_005245247 XP_005245304 XM_005245248 XP_005245305 XM_005245249 XP_005245306 XM_006711366 XP_006711429 XM_006711367 XP_006711430 XM_006711368 XP_006711431 XM_006711369 XP_006711432 XM_006711370 XP_006711433 XM_006711371 XP_006711434 XM_011509604 XP_011507906 XM_011509605 XP_011507907 XM_011509606 XP_011507908 XM_011509607 XP_011507909 XM_011509608 XP_011507910 XM_011509609 XP_011507911 XR_921823 NM_001199261 NP_001186190 NM_001199262 NP_001186191 NM_001199263 NP_001186192 NM_015984 NP_057068 NR_037607
Function Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1. {ECO:0000269|PubMed:16906146, ECO:0000269|PubMed:18922472}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18922472}. Nucleus {ECO:0000269|PubMed:18922472}. Note=Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus.

UCH-L5 (C-4) - sc-271002 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UCH-L5 (C-4): sc-271002. Western blot analysis of UCH-L5 expression in IMR-32 (A) and U-87 MG (B) whole cell lysates.

UCH-L5 (H-110) - sc-98673 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
UCH-L5 (H-110): sc-98673. Western blot analysis of UCH-L5 expression in non-transfected: sc-110760 (A) and human UCH-L5 transfected: sc-113202 (B) 293 whole cell lysates and mouse brain tissue extract (C).

UCH-L5 (N-16) - sc-83058 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UCH-L5 (N-16): sc-83058. Western blot analysis of UCH-L5 expression in IMR-32 (A) and U-87 MG (B) whole cell lysates.

Anti-UCH37 antibody - ab38528 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-UCH37 antibody (ab38528) + mouse kidney tissue lysate

Anti-UCH37 antibody [854CT5.5.6] - N-terminal - ab180020 from Abcam

Prices $376.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Clone 854CT5.5.6
All lanes : Anti-UCH37 antibody [854CT5.5.6] - N-terminal (ab180020) at 1/1000 dilutionLane 1 : 293 cell line lysateLane 2 : HeLa cell line lysateLane 3 : 293T cell line lysateLysates/proteins at 35 µg per lane.developed using the ECL technique

Anti-UCH37 antibody [EP4897] - ab133508 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP4897
All lanes : Anti-UCH37 antibody [EP4897] (ab133508) at 1/10000 dilutionLane 1 : 293T lysateLane 2 : Fetal kidney lysateLane 3 : Jar lysateLane 4 : SH-SY5Y lysateLane 5 : NCCIT lysateLysates/proteins at 10 µg per lane.SecondaryGoat-anti-rabbit HRP at 1/2000 dilution

Anti-UCH37 antibody [EPR4896] - ab124931 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4896
All lanes : Anti-UCH37 antibody [EPR4896] (ab124931) at 1/1000 dilutionLane 1 : Human fetal kidney cell lysatesLane 2 : 293T cell lysatesLane 3 : NCCIT cell lysatesLane 4 : SH-SY5Y cell lysatesLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-UCHL5 / UCH37 Antibody (Internal, clone EPR4896) - LS-C138311 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4896
IHC of paraffin-embedded human kidney tissue using anti-UCH37antibody.

Anti-UCHL5 / UCH37 Antibody (N-Terminus, APC) - LS-C284027 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (N-Terminus, Biotin) - LS-C284028 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (N-Terminus, Azide-free, HRP) - LS-C284029 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (N-Terminus, FITC) - LS-C284030 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (N-Terminus, PE) - LS-C284031 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (aa175-225) - LS-C290745 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (aa136-164) - LS-C157014 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UCHL5 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The UCHL5 antibody detected the UCHL5 protein (arrow).

Anti-UCHL5 / UCH37 Antibody (aa279-329) - LS-C290746 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (aa66-268, Biotin) - LS-C297191 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (aa56-87) - LS-C99521 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HE staining of frozen human ovarian cancer tissue reacted with the primary antibody at a 1:250 dilution. Levels using the antibody on frozen tissue array (A )correlated well with the mRNA expression levels detected by Agilent expression microarray (B). This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. 60X magnification. Data courtesy of Marlena Fejzo, University of California, Los Angeles.

Anti-UCHL5 / UCH37 Antibody (aa2-316, Biotin) - LS-C298785 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (aa27-246, Biotin) - LS-C297201 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (aa150-200) - LS-C290744 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse UCH37 by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, HeLa, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-UCH37 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-UCHL5 / UCH37 Antibody (aa2-316, FITC) - LS-C302390 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (aa66-268, FITC) - LS-C304045 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (aa27-246, FITC) - LS-C304117 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UCHL5 / UCH37 Antibody (Internal, clone EP4897) - LS-C138671 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP4897
IHC of paraffin-embedded human kidney tissue using anti-UCHL5 / UCH37 antibody.
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