| Gene Symbol |
PDE7B
|
| Entrez Gene |
27115
|
| Alt Symbol |
bA472E5.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphodiesterase 7B
|
| Other Description |
cAMP-specific 3',5'-cyclic phosphodiesterase 7B|high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase|rolipram-insensitive phosphodiesterase type 7
|
| Swissprots |
Q9NP56 Q5W154
|
| Accessions |
CAC22485 CBX54288 CDL93465 CDL96993 EAW47956 EAW47957 Q9NP56 AB038040 BAA96537 AB209990 BAE06072 AF086025 AJ251860 CAB92441 AK290582 BAF83271 BC070267 AAH70267 BC075082 AAH75082 BC075083 AAH75083 EF108327 ABL14249 EU446993 ABZ92522 XM_005266931 XP_005266988 XM_011535755 XP_011534057 NM_018945 NP_061818
|
| Function |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
|
| Tissue Specificity |
Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas.
|
| Top Pathways |
Morphine addiction, Purine metabolism
|