Gene Symbol | PDE7B |
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Entrez Gene | 27115 |
Alt Symbol | bA472E5.1 |
Species | Human |
Gene Type | protein-coding |
Description | phosphodiesterase 7B |
Other Description | cAMP-specific 3',5'-cyclic phosphodiesterase 7B|high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase|rolipram-insensitive phosphodiesterase type 7 |
Swissprots | Q9NP56 Q5W154 |
Accessions | CAC22485 CBX54288 CDL93465 CDL96993 EAW47956 EAW47957 Q9NP56 AB038040 BAA96537 AB209990 BAE06072 AF086025 AJ251860 CAB92441 AK290582 BAF83271 BC070267 AAH70267 BC075082 AAH75082 BC075083 AAH75083 EF108327 ABL14249 EU446993 ABZ92522 XM_005266931 XP_005266988 XM_011535755 XP_011534057 NM_018945 NP_061818 |
Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain. |
Tissue Specificity | Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas. |
Top Pathways | Morphine addiction, Purine metabolism |
PDE7B CRISPR/Cas9 KO Plasmid (h) - sc-411961 from Santa Cruz Biotechnology
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PDE7B HDR Plasmid (h) - sc-411961-HDR from Santa Cruz Biotechnology
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PDE7B Double Nickase Plasmid (h) - sc-411961-NIC from Santa Cruz Biotechnology
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PDE7B Double Nickase Plasmid (h2) - sc-411961-NIC-2 from Santa Cruz Biotechnology
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PDE7B CRISPR Activation Plasmid (h) - sc-411961-ACT from Santa Cruz Biotechnology
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PDE7B CRISPR Activation Plasmid (h2) - sc-411961-ACT-2 from Santa Cruz Biotechnology
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PDE7B Lentiviral Activation Particles (h) - sc-411961-LAC from Santa Cruz Biotechnology
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PDE7B Lentiviral Activation Particles (h2) - sc-411961-LAC-2 from Santa Cruz Biotechnology
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PDE7B siRNA (h) - sc-41614 from Santa Cruz Biotechnology
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PDE7B shRNA Plasmid (h) - sc-41614-SH from Santa Cruz Biotechnology
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PDE7B shRNA (h) Lentiviral Particles - sc-41614-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN16546 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16546 from Sigma-Aldrich
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PDE7B siRNA (Human) - CRH8973 from Cohesion Biosciences
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PDE7B RNAi - H00027115-R01 from Novus Biologicals
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shRNA set against Human PDE7B (NM_018945.3) - SHH372580 from Creative biogene
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shRNA set against Human PDE7B(NM_018945.3) - SHR101280 from Creative biogene
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Human PDE7B siRNA - orb269475 from Biorbyt
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PDE7B shRNA Plasmid (Human) - CHH8973 from Cohesion Biosciences
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PDE7B miRNA 3'UTR clone - MiUTR1H-07717 from Creative biogene
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