| Gene Symbol |
SLC25A36
|
| Entrez Gene |
55186
|
| Alt Symbol |
PNC2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 25 (pyrimidine nucleotide carrier), member 36
|
| Other Description |
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36|solute carrier family 25 member 36|solute carrier family 25, member 36
|
| Swissprots |
Q9H0G8 Q9NVN5 A8MYF7 Q05CY1 Q96CQ1
|
| Accessions |
EAW79011 EAW79012 EAW79013 Q96CQ1 AK001480 BAA91715 AK296785 BAG59363 AL049246 AL136803 CAB66737 BC014064 AAH14064 BC019859 BC036272 BM552452 BQ718950 BQ771812 DA593079 EU831411 ACE87098 EU831504 ACE86423 XM_005247575 XP_005247632 XM_006713685 XP_006713748 XM_011512951 XP_011511253 XM_011512952 XP_011511254 XM_011512953 XP_011511255 XR_924150 XR_924151 XR_924152 XR_924153 XR_924154 XR_924155 XR_924156 XR_924157 NM_001104647 NP_001098117 NM_018155 NP_060625
|
| Function |
Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by uniport and antiport mechanism. Also transports guanine but not adenine (deoxy)nucleotides. Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10- phenanthroline, tannic acid, and mercurials (mercury dichloride, Mersalyl acid, p-hydroxymercuribenzoate). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration. {ECO:0000269|PubMed:25320081}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000305|PubMed:25320081}; Multi-pass membrane protein {ECO:0000255}.
|
| Tissue Specificity |
Expressed at moderate level. {ECO:0000269|PubMed:17210862}.
|
