SPTBN1

Gene Symbol SPTBN1
Entrez Gene 6711
Alt Symbol ELF, HEL102, SPTB2, betaSpII
Species Human
Gene Type protein-coding
Description spectrin, beta, non-erythrocytic 1
Other Description beta-G spectrin|beta-II spectrin|beta-fodrin|beta-spectrin 2|beta-spectrin II|beta-spectrin non-erythrocytic 1|embryonic liver beta-fodrin|epididymis luminal protein 102|fodrin beta chain|spectrin beta chain, brain 1|spectrin beta chain, non-erythrocytic 1|spectrin, non-erythroid beta chain 1
Swissprots Q59ER3 Q01082 Q8IX99 Q53R99 O60837 B2RP63 Q16057
Accessions AAX93104 AAY24229 CAB91088 CBX47472 CBX47473 EAX00137 EAX00138 EAX00139 EAX00140 EAX00141 EAX00142 EAX00143 EAX00144 EAX00145 EAX00146 EAX00147 Q01082 AB209551 BAD92788 AB209748 BAD92985 AB371586 BAG48315 AF218848 AAL56651 AF327441 AAO15362 AJ005694 CAA06678 AK023762 AK025071 AK093946 AK295570 BAG58470 AL117605 BC009640 BC032061 BC137282 AAI37283 BC137283 AAI37284 BM679686 BP218428 BP312037 CR980403 EU794662 ACJ13716 JQ599728 AFX60968 S65762 AAB28324 XM_005264517 XP_005264574 XM_005264518 XP_005264575 XM_006712087 XP_006712150 NM_003128 NP_003119 NM_178313 NP_842565
Function Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250}. Note=Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes. {ECO:0000250}.
Tissue Specificity Isoform 2 is present in brain, lung and kidney (at protein level). {ECO:0000269|PubMed:11665863}.

Spectrin β II (A-16) - sc-26913 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
spectrin β II (A-16): sc-26913. Western blot analysis of spectrin β II expression in SK-N-MC (A) and HeLa (B) whole cell lysates and rat cerebellum (C) and rat brain (D) tissue extracts.

spectrin β II (C-19) - sc-7468 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
spectrin β II (C-19): sc-7468. Immunofluorescence staining of methanol-fixed SK-N-SH cells showing membrane and cytoplasmic staining.

spectrin β II (H-125) - sc-28272 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
spectrin β II (H-125): sc-28272. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubuli at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

spectrin β II (K-17) - sc-26915 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

spectrin β II (42) - sc-136074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
spectrin β II (42): sc-136074. Western blot analysis of spectrin β II expression in Jurkat whole cell lysate.

Anti-SPTBN1 antibody - ab72239 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma tissue labelling SPTBN1 with ab72239 at 1/1000 (0.2µg/ml). Detection: DAB.

Anti-SPTBN1 antibody - ab138274 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SPTBN1 antibody (ab138274) at 1/500 dilution + Jurkat cell lysate at 30 µg

Anti-SPTBN1 antibody - ab84498 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84498, at 1/250 dilution, staining SPTBN1 in formalin-fixed, paraffin-embedded human prostate adenocarcinoma by Immunohistochemistry, using DAB staining.

Anti-SPTBN1 antibody [EPR5869] - ab124888 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5869
ab124888, at 1/250 dilution, staining SPTBN1 in paraffin-embedded Human kidney tissue by Immunohistochemistry.

Anti-SPTBN1 / ELF Antibody (aa2150-2200) - LS-C89227 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-SPTBN1 / ELF Antibody (aa638-687) - LS-C200720 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from Jurkat cells using SPTBN1 antibody.

Anti-SPTBN1 / ELF Antibody (C-Terminus) - LS-C187253 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human NCI-H226. SPTBN1 antibody dilution 1.0 ug/ml.

Anti-SPTBN1 / ELF Antibody (aa2150-2200) - LS-C286426 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SPTBN1 by Immunohistochemistry. Sample: FFPE section of human colon adenocarcinoma. Antibody: Affinity purified rabbit anti-SPTBN1 used at a dilution of 1:250.

Anti-SPTBN1 / ELF Antibody (aa2100-2150) - LS-C286035 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SPTBN1 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-SPTBN1 used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.

Anti-SPTBN1 / ELF Antibody (Internal, clone EPR5869) IHC-plus™ - LS-B7127 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5869
Anti-SPTBN1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7127 dilution 1:100.

Anti-SPTBN1 / ELF Antibody (aa2150-2200) - LS-C287769 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SPTBN1 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-SPTBN1 used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.

Anti-SPTBN1 / ELF Antibody (aa651-700) - LS-C120415 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from COLO cells, using SPTBN1 Antibody. The lane on the right is treated with the synthesized peptide.

Spectrin beta 2 Antibody - NB100-40828 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Spectrin beta 2 Antibody [NB100-40828] - Detection of Human and Mouse SPTBN1 on HeLa whole cell lysate using NB100-40828. SPTBN1 was also immunoprecipitated by rabbit anti-SPTBN1 antibody NB100-40829.

Spectrin beta 2 Antibody - NB100-40829 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Spectrin beta 2 Antibody [NB100-40829] - Detection of Human SPTBN1 on HeLa whole cell lysate using NB100-40829. SPTBN1 was also immunoprecipitated by rabbit anti-SPTBN1 antibody NB100-40828.

Spectrin beta 2 Antibody - NBP1-86088 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Spectrin beta 2 Antibody [NBP1-86088] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue

Spectrin beta 2 Antibody - NBP1-01012 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Spectrin beta 2 Antibody [NBP1-01012] - Analysis of Spectrin Beta II pAb in extracts from COLO cells.

Anti-SPTBN1 antibody produced in rabbit - HPA013149 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SPTBN1: <B>Cat. No. HPA013149</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney shows strong cytoplasmic and membranous positivity in cells in tubules and cells in glomeruli.

Anti-SPTBN1 antibody produced in rabbit - HPA012685 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SPTBN1: <B>Cat. No. HPA012685</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human gall bladder shows moderate cytoplasmic and membranous positivity in glandular cells.

SPTBN1 Antibody - C-terminal region (ARP61837_P050) - ARP61837_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SPTBN1 Antibody (OAAF04330) - OAAF04330 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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