| Gene Symbol | GMPR2 |
|---|---|
| Entrez Gene | 51292 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | guanosine monophosphate reductase 2 |
| Other Description | GMP reductase 2|guanosine 5'-monophosphate oxidoreductase 2|guanosine monophosphate reductase isolog |
| Swissprots | Q9P2T1 Q86T14 Q6IAJ8 Q567T0 D3DS66 |
| Accessions | EAW66051 EAW66052 EAW66053 EAW66054 EAW66055 EAW66056 EAW66057 EAW66058 Q9P2T1 AB032903 BAA93080 AF086919 AAP97149 AF135159 AAG09132 AF419346 AAN32701 AK226166 AV660418 BC003053 AAH03053 BC008021 AAH08021 BC009832 AAH09832 BC093039 AAH93039 BE003291 BI259066 BP347823 BX161436 CAD61908 BX161518 CAD61951 BX247993 CAD62327 BX375671 CA447126 CR457156 CAG33437 HQ447583 ADQ32069 XM_005267740 XP_005267797 XM_005267741 XP_005267798 XM_005267742 XP_005267799 XM_006720165 XP_006720228 NM_001002000 NP_001002000 NM_001002001 NP_001002001 NM_001002002 NP_001002002 NM_001283021 NP_001269950 NM_001283022 NP_001269951 NM_001283023 NP_001269952 NM_016576 NP_057660 NR_104265 |
| Function | Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation. {ECO:0000269|PubMed:12009299, ECO:0000269|PubMed:12669231, ECO:0000269|PubMed:16359702, ECO:0000269|PubMed:22037469}. |
| Tissue Specificity | Highly expressed in heart, skeletal muscle, kidney, brain, liver, prostate, spleen, placenta, testis and ovary. Low expression in colon, thymus and peripheral blood leukocytes. {ECO:0000269|PubMed:12009299, ECO:0000269|PubMed:12669231}. |
| Top Pathways | Purine metabolism |
Human-GMPR2-cDNA-Clone - DC02310 from Abgent, a WuXi AppTec company
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GMPR2 - MBS1271851 from MyBioSource
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GMPR2 - MBS1270001 from MyBioSource
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Human GMPR2 cDNA clone(NM_016576.3) - CDFG000564 from Creative Biomart
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Human GMPR2 cDNA clone(NM_001002000.1) - CDFH007695 from Creative Biomart
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Human GMPR2 cDNA clone(NM_001002000.1) - CDFH007696 from Creative Biomart
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Human GMPR2 cDNA clone(NM_001002002.1) - CDFH007697 from Creative Biomart
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Human GMPR2 cDNA clone(NM_001002001.1) - CDFH007698 from Creative Biomart
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Human GMPR2 ORF Clone(NM_016576.3) - CDCL164874 from Creative Biomart
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Human GMPR2 ORF Clone(NM_001002000.1) - CDCL164875 from Creative Biomart
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Human GMPR2 ORF Clone(NM_016576.3) - CDCR301470 from Creative Biomart
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Human GMPR2 ORF Clone(NM_016576.3) - CDCR301471 from Creative Biomart
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Human GMPR2 ORF Clone(NM_016576.3) - CDCR301472 from Creative Biomart
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Human GMPR2 ORF Clone(NM_001002000.1) - CDCR338589 from Creative Biomart
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Human GMPR2 ORF Clone(NM_001002000.1) - CDCR338590 from Creative Biomart
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Human GMPR2 ORF Clone(NM_001002000.1) - CDCR338621 from Creative Biomart
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Human GMPR2 ORF Clone(NM_001002001.1) - CDCR338622 from Creative Biomart
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Human GMPR2 ORF Clone(NM_001002001.1) - CDCR338623 from Creative Biomart
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Human GMPR2 ORF Clone(NM_001002001.1) - CDCR338624 from Creative Biomart
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Human GMPR2 ORF Clone(NM_001002002.1) - CDCR338625 from Creative Biomart
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Human GMPR2 ORF Clone(NM_001002002.1) - CDCR338626 from Creative Biomart
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Human GMPR2 ORF Clone(NM_016576.3) - CDCR301470 from Creative biogene
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Human GMPR2 ORF Clone(NM_001002000.1) - CDCR338589 from Creative biogene
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Human GMPR2 ORF Clone(NM_001002001.1) - CDCR338622 from Creative biogene
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Human GMPR2 ORF Clone(NM_001002002.1) - CDCR338625 from Creative biogene
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