Gene Symbol | MYOZ2 |
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Entrez Gene | 51778 |
Alt Symbol | C4orf5, CMH16, CS-1 |
Species | Human |
Gene Type | protein-coding |
Description | myozenin 2 |
Other Description | FATZ-related protein 2|calcineurin-binding protein calsarcin-1|muscle-specific protein|myozenin-2 |
Swissprots | Q9HB92 Q9NPC6 O43415 |
Accessions | AAG13932 CCQ43545 EAW73662 Q9NPC6 AF007160 AAC19160 AF249873 AAF63623 AJ252149 CAB92965 AK313856 BAG36584 AY013295 AAG38938 BC005195 AAH05195 BC017402 AAH17402 BC020932 AAH20932 BM091578 BP370492 BT007214 AAP35878 XM_006714234 XP_006714297 NM_016599 NP_057683 |
Function | Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. |
Subcellular Location | Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Colocalizes with ACTN1 and PPP3CA at the Z- line of heart and skeletal muscle. {ECO:0000250}. |
Tissue Specificity | Expressed specifically in heart and skeletal muscle. {ECO:0000250|UniProtKB:Q9JJW5, ECO:0000269|PubMed:11114196, ECO:0000269|PubMed:11161785}. |
Myozenin 2 CRISPR/Cas9 KO Plasmid (h) - sc-416593 from Santa Cruz Biotechnology
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Myozenin 2 HDR Plasmid (h) - sc-416593-HDR from Santa Cruz Biotechnology
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Myozenin 2 Double Nickase Plasmid (h) - sc-416593-NIC from Santa Cruz Biotechnology
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Myozenin 2 Double Nickase Plasmid (h2) - sc-416593-NIC-2 from Santa Cruz Biotechnology
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Myozenin 2 CRISPR Activation Plasmid (h) - sc-416593-ACT from Santa Cruz Biotechnology
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Myozenin 2 CRISPR Activation Plasmid (h2) - sc-416593-ACT-2 from Santa Cruz Biotechnology
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Myozenin 2 Lentiviral Activation Particles (h) - sc-416593-LAC from Santa Cruz Biotechnology
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Myozenin 2 Lentiviral Activation Particles (h2) - sc-416593-LAC-2 from Santa Cruz Biotechnology
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Myozenin 2 siRNA (h) - sc-45710 from Santa Cruz Biotechnology
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Myozenin 2 shRNA Plasmid (h) - sc-45710-SH from Santa Cruz Biotechnology
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Myozenin 2 shRNA (h) Lentiviral Particles - sc-45710-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU143811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14879 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14879 from Sigma-Aldrich
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MYOZ2 siRNA (Human) - CRH9946 from Cohesion Biosciences
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shRNA set against Human MYOZ2 (NM_016599.4) - SHH348476 from Creative biogene
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Human MYOZ2 siRNA - orb270448 from Biorbyt
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MYOZ2 shRNA Plasmid (Human) - CHH9946 from Cohesion Biosciences
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MYOZ2 miRNA 3'UTR clone - MiUTR3H-07821 from Creative biogene
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