| Gene Symbol |
Pla2g2d
|
| Entrez Gene |
18782
|
| Alt Symbol |
Splash, mGIID
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
phospholipase A2, group IID
|
| Other Description |
GIID sPLA2|PLA2IID|group IID secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2D|sPLA2-IID|secretory-type PLA, stroma-associated homolog
|
| Swissprots |
Q9WVF6 Q9JLK0 Q3V4B8
|
| Accessions |
AAF09019 EDL13277 EDL13278 Q9WVF6 AF112983 AAD51391 AF124374 AAD42773 AF169407 AAF42987 AF169408 AAF42988 AK004232 BAE43166 AK018005 BAB31033 AK157392 BAE34077 AK158364 BAE34473 AK171797 BAE42668 AK172367 BAE42967 BC111806 AAI11807 XM_006538657 XP_006538720 NM_011109 NP_035239
|
| Function |
PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2- linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined.
|
| Subcellular Location |
Isoform 1: Secreted {ECO:0000305}.
|
| Tissue Specificity |
Expressed in several tissues including pancreas, spleen, thymus, skin, lung, and ovary.
|
| Top Pathways |
Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism
|