| Gene Symbol |
MARVELD1
|
| Entrez Gene |
83742
|
| Alt Symbol |
GB14, MARVD1, MRVLDC1, bA548K23.8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MARVEL domain containing 1
|
| Other Description |
MARVEL (membrane-associating) domain containing 1|MARVEL domain-containing protein 1|putative MARVEL domain-containing protein 1
|
| Swissprots |
Q9BSK0
|
| Accessions |
EAW49903 Q9BSK0 AF325259 AI347102 AK025996 AK027093 BC004995 BC062544 CF125014 NM_031484 NP_113672
|
| Function |
Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration. {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000269|PubMed:19364627}. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed in normal tissues. Down- regulated in multiple primary tumors. {ECO:0000269|PubMed:19364627}.
|