Gene Symbol | MARVELD1 |
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Entrez Gene | 83742 |
Alt Symbol | GB14, MARVD1, MRVLDC1, bA548K23.8 |
Species | Human |
Gene Type | protein-coding |
Description | MARVEL domain containing 1 |
Other Description | MARVEL (membrane-associating) domain containing 1|MARVEL domain-containing protein 1|putative MARVEL domain-containing protein 1 |
Swissprots | Q9BSK0 |
Accessions | EAW49903 Q9BSK0 AF325259 AI347102 AK025996 AK027093 BC004995 BC062544 CF125014 NM_031484 NP_113672 |
Function | Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000269|PubMed:19364627}. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization (By similarity). {ECO:0000250}. |
Tissue Specificity | Widely expressed in normal tissues. Down- regulated in multiple primary tumors. {ECO:0000269|PubMed:19364627}. |
MARVELD1 CRISPR/Cas9 KO Plasmid (h) - sc-413502 from Santa Cruz Biotechnology
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MARVELD1 HDR Plasmid (h) - sc-413502-HDR from Santa Cruz Biotechnology
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MARVELD1 Double Nickase Plasmid (h) - sc-413502-NIC from Santa Cruz Biotechnology
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MARVELD1 Double Nickase Plasmid (h2) - sc-413502-NIC-2 from Santa Cruz Biotechnology
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MARVELD1 CRISPR Activation Plasmid (h) - sc-413502-ACT from Santa Cruz Biotechnology
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MARVELD1 CRISPR Activation Plasmid (h2) - sc-413502-ACT-2 from Santa Cruz Biotechnology
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MARVELD1 Lentiviral Activation Particles (h) - sc-413502-LAC from Santa Cruz Biotechnology
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MARVELD1 Lentiviral Activation Particles (h2) - sc-413502-LAC-2 from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN13048 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13048 from Sigma-Aldrich
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MARVELD1 siRNA (Human) - CRJ3186 from Cohesion Biosciences
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shRNA set against Human MARVELD1 (NM_031484.3) - SHH338427 from Creative biogene
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Human MARVELD1 siRNA - orb273687 from Biorbyt
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MARVELD1 shRNA Plasmid (Human) - CHJ3186 from Cohesion Biosciences
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MARVELD1 miRNA 3'UTR clone - MiUTR4H-TG05383 from Creative biogene
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