Gene Symbol | CNDP2 |
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Entrez Gene | 55748 |
Alt Symbol | CN2, CPGL, HEL-S-13, HsT2298, PEPA |
Species | Human |
Gene Type | protein-coding |
Description | CNDP dipeptidase 2 (metallopeptidase M20 family) |
Other Description | cytosolic non-specific dipeptidase|cytosolic nonspecific dipeptidase|epididymis secretory protein Li 13|glutamate carboxypeptidase-like protein 1|peptidase A |
Swissprots | Q9NVB4 Q9BQ94 B3KUG4 Q8WY59 Q96KP4 |
Accessions | CAD56843 CCQ43593 EAW66550 EAW66551 EAW66552 EAW66553 EAW66554 EAW66555 EAW66556 EAW66557 EAW66558 Q96KP4 AF258592 AAG23795 AJ347717 CAC69883 AK001262 BAA91587 AK001692 BAA91840 AK001983 BAA92018 AK024471 BAB15761 AK092863 AK097155 BAG53426 AK298309 BAG60563 AK300904 BAG62540 BC001375 AAH01375 BC003176 AAH03176 BM675304 BQ183399 DC313148 DC392026 EU794600 ACJ13654 XM_005266728 XP_005266785 XM_006722503 XP_006722566 XM_011526071 XP_011524373 XM_011526072 XP_011524374 XM_011526073 XP_011524375 NM_001168499 NP_001161971 NM_018235 NP_060705 |
Function | Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. {ECO:0000269|PubMed:17121880, ECO:0000269|PubMed:19346245}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12473676, ECO:0000269|PubMed:17121880}. |
Tissue Specificity | Isoform 1 is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. {ECO:0000269|PubMed:12473676, ECO:0000269|PubMed:17121880}. |
Top Pathways | Arginine and proline metabolism, Histidine metabolism, beta-Alanine metabolism |
CNDP2 (K-18) - sc-82564 from Santa Cruz Biotechnology
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Anti-CNDP2 antibody - ab101406 from Abcam
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Anti-CNDP2 antibody - ab103612 from Abcam
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Anti-CNDP2 antibody - ab88939 from Abcam
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Anti-CNDP2 antibody - ab130476 from Abcam
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Anti-CNDP2 antibody - ab57649 from Abcam
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Anti-CNDP2 antibody [6D3] - ab119191 from Abcam
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Anti-CNDP2 antibody [AT15E5] - ab167468 from Abcam
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Anti-CNDP2 antibody [EPR13256] - N-terminal - ab181044 from Abcam
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Anti-CNDP2 antibody [EPR13257(B)] - ab176332 from Abcam
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Anti-CNDP2 Antibody (clone 8A2) - LS-C173113 from LifeSpan Bioscience
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Anti-CNDP2 Antibody - LS-C309944 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (HRP) - LS-C317536 from LifeSpan Bioscience
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Anti-CNDP2 Antibody - LS-C317537 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (FITC) - LS-C317538 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (aa395-444) - LS-C117201 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (Biotin) - LS-C317539 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (aa347-375) - LS-C168873 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (aa347-375) - LS-C320475 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (clone AT15E5) IHC-plus™ - LS-B8974 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (clone 6D3) - LS-C173345 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (clone 1A6) - LS-C139298 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (aa347-375, APC) - LS-C221824 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (aa347-375, AP) - LS-C221823 from LifeSpan Bioscience
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Anti-CNDP2 Antibody (aa347-375, FITC) - LS-C221826 from LifeSpan Bioscience
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