Gene Symbol |
FSD1
|
Entrez Gene |
79187
|
Alt Symbol |
GLFND, MIR1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
fibronectin type III and SPRY domain containing 1
|
Other Description |
MID1-related protein 1|fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1|fibronectin type 3 and SPRY domain containing 1|fibronectin type III and SPRY domain-containing protein 1|microtubule-associated protein GLFND|midline 1-related protein 1
|
Swissprots |
Q9HAG4 Q9BTV5 B2RDT0 Q9BXN0
|
Accessions |
EAW69236 EAW69237 EAW69238 Q9BTV5 AF316829 AAK26747 AK021750 BAB13885 AK295523 BAG58437 AK303606 BAG64621 AK315661 BAG38027 AY032617 AAK51145 BC003124 AAH03124 BC016442 CA749067 DA690632 DQ891833 ABM82759 DQ895020 ABM85946 XM_005259644 XP_005259701 NM_024333 NP_077309
|
Function |
May be involved in microtubule organization and stabilization. {ECO:0000269|PubMed:12154070, ECO:0000269|PubMed:12445389}.
|
Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
|
Tissue Specificity |
Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord. {ECO:0000269|PubMed:11267680, ECO:0000269|PubMed:12154070}.
|