Gene Symbol | FSD1 |
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Entrez Gene | 79187 |
Alt Symbol | GLFND, MIR1 |
Species | Human |
Gene Type | protein-coding |
Description | fibronectin type III and SPRY domain containing 1 |
Other Description | MID1-related protein 1|fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1|fibronectin type 3 and SPRY domain containing 1|fibronectin type III and SPRY domain-containing protein 1|microtubule-associated protein GLFND|midline 1-related protein 1 |
Swissprots | Q9HAG4 Q9BTV5 B2RDT0 Q9BXN0 |
Accessions | EAW69236 EAW69237 EAW69238 Q9BTV5 AF316829 AAK26747 AK021750 BAB13885 AK295523 BAG58437 AK303606 BAG64621 AK315661 BAG38027 AY032617 AAK51145 BC003124 AAH03124 BC016442 CA749067 DA690632 DQ891833 ABM82759 DQ895020 ABM85946 XM_005259644 XP_005259701 NM_024333 NP_077309 |
Function | May be involved in microtubule organization and stabilization. {ECO:0000269|PubMed:12154070, ECO:0000269|PubMed:12445389}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle. |
Tissue Specificity | Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord. {ECO:0000269|PubMed:11267680, ECO:0000269|PubMed:12154070}. |
FSD1 CRISPR/Cas9 KO Plasmid (h) - sc-406328 from Santa Cruz Biotechnology
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FSD1 HDR Plasmid (h) - sc-406328-HDR from Santa Cruz Biotechnology
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FSD1 Double Nickase Plasmid (h) - sc-406328-NIC from Santa Cruz Biotechnology
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FSD1 Double Nickase Plasmid (h2) - sc-406328-NIC-2 from Santa Cruz Biotechnology
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FSD1 CRISPR Activation Plasmid (h) - sc-406328-ACT from Santa Cruz Biotechnology
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FSD1 CRISPR Activation Plasmid (h2) - sc-406328-ACT-2 from Santa Cruz Biotechnology
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FSD1 Lentiviral Activation Particles (h) - sc-406328-LAC from Santa Cruz Biotechnology
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FSD1 Lentiviral Activation Particles (h2) - sc-406328-LAC-2 from Santa Cruz Biotechnology
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FSD1 siRNA (h) - sc-97218 from Santa Cruz Biotechnology
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FSD1 shRNA Plasmid (h) - sc-97218-SH from Santa Cruz Biotechnology
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FSD1 shRNA (h) Lentiviral Particles - sc-97218-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU003301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8964 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8964 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00860 from Sigma-Aldrich
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FSD1 siRNA (Human) - CRJ2354 from Cohesion Biosciences
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FSD1 - MBS8215735 from MyBioSource
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FSD1 CRISPR/Cas9 KO Plasmid (h2) - sc-406328-KO-2 from Santa Cruz Biotechnology
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FSD1 HDR Plasmid (h2) - sc-406328-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human FSD1 (NM_024333.2) - SHH297345 from Creative biogene
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Human FSD1 siRNA - orb272855 from Biorbyt
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FSD1 shRNA Plasmid (Human) - CHJ2354 from Cohesion Biosciences
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FSD1 miRNA 3'UTR clone - MiUTR3H-10826 from Creative biogene
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