BAAT

Gene Symbol BAAT
Entrez Gene 570
Alt Symbol BACAT, BAT
Species Human
Gene Type protein-coding
Description bile acid CoA:amino acid N-acyltransferase
Other Description bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)|bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)|bile acid-CoA:amino acid N-acyltransferase|long-chain fatty-acyl-CoA hydrolase
Swissprots Q14032 Q96L31 Q3B7W9
Accessions EAW58943 EAW58944 EAW58945 EAW58946 Q14032 AK315347 BC009567 AAH09567 BC039200 BC107424 AAI07425 BG565737 CB154234 CR541918 CAG46716 DQ891910 ABM82836 DQ895095 ABM86021 H62757 L34081 AAC37550 NM_001127610 NP_001121082 NM_001701 NP_001692
Function Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very lo
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12810727}.
Tissue Specificity Expressed in liver, gallbladder mucosa and pancreas. {ECO:0000269|PubMed:12810727, ECO:0000269|PubMed:2037576}.
Top Pathways Primary bile acid biosynthesis, Peroxisome, Bile secretion, Taurine and hypotaurine metabolism, Biosynthesis of unsaturated fatty acids

BAAT (ZA-18) - sc-100475 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
BAAT (ZA-18): sc-100475. Western blot analysis of BAAT expression in Hep G2 whole cell lysate.

Anti-BAAT antibody - ab83882 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BAAT antibody (ab83882) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BAAT antibody - ab97455 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BAAT antibody (ab97455) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-BAAT antibody - ab154918 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BAAT antibody (ab154918) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : HeLa whole cell lysateLysates/proteins at 30 µg per lane.

Anti-BAAT antibody - ab54812 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BAAT / BAT Antibody (aa139-415) - LS-C186148 from LifeSpan Bioscience

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BAAT / BAT Antibody (N-Terminus) - LS-C102179 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
BAAT antibody LS-C102179 Western blot of Fetal Liver lysate.

Anti-BAAT / BAT Antibody (clone 5B6) - LS-C196730 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B6
BAAT monoclonal antibody (M02), clone 5B6 Western Blot analysis of BAAT expression in HepG2.

BAAT Antibody - NBP2-14344 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BAAT Antibody [NBP2-14344] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue

BAAT Antibody - NBP2-15535 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BAAT Antibody [NBP2-15535] - Sample (30 ug of whole cell lysate) A: A431 B: HeLa 10% SDS PAGE gel, diluted at 1:1000.

BAAT Antibody (5B6) - H00000570-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B6
Western Blot: BAAT Antibody (5B6) [H00000570-M02] - BAAT monoclonal antibody (M02), clone 5B6 Analysis of BAAT expression in HepG2.

BAAT Antibody - NBP1-32913 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: BAAT Antibody [NBP1-32913] - Western blot analysis of BAAT on Hep G2 lysate using NBP1-32913 at a dilution of 1:1000. 30ug of whole cell lysate loaded on 10% SDS PAGE gel.

BAAT Antibody - H00000570-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

BAAT Polyclonal Antibody - bs-5040R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human liver carcinoma labeled with Anti-BAAT Polyclonal Antibody, Unconjugated (bs-5040R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Monoclonal Anti-BAAT antibody produced in mouse - SAB1403597 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E4
<B>Immunoblotting</B><BR/>Monoclonal Anti-BAAT: <B>Cat. No. SAB1403597</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~46.3 kDa using HL~60 lysate.

Anti-BAAT antibody produced in rabbit - HPA021330 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BAAT:<B>Cat. No. HPA021330</B>: Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Monoclonal Anti-BAAT antibody produced in mouse - WH0000570M2 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B6
<B>Immunoblotting</B><BR/>Monoclonal Anti-BAAT, <B>Cat. No. WH0000570M2</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~46.3 kDa using HepG2 lysate.

Anti-BAAT (326-340) antibody produced in rabbit - B8812 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human BAAT was separated on SDS-PAGE, blotted with Anti-BAAT (326-340) (<B>Cat. No. B8812</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1.Antibody dilution 1:500 <BR/>2. Antibody dilution 1:500 + BAAT immunizing peptide (human, 326-340)

Anti-BAAT antibody produced in rabbit - SAB2100199 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-BAAT: <B>Cat. No.SAB2100199</B>: BAAT in Fetal Liver tissue lysate with BAAT antibody at 1.0 μg/mL.

Anti-BAAT (41-55) antibody produced in rabbit - B8687 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human BAAT was separated on SDS-PAGE, blotted with Anti-BAAT (41-55) (<B>Cat. No. B8687</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

BAAT antibody - N-terminal region (ARP45686_P050) - ARP45686_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BAAT-Antibody-monoclonal-M02 - AT1257a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B6
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .

BAAT antibody - GTX110298 from GeneTex

Prices $149.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

BAAT antibody - GTX109917 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-BAAT antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX109917
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