Gene Symbol | ACO2 |
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Entrez Gene | 50 |
Alt Symbol | ACONM, ICRD, OCA8 |
Species | Human |
Gene Type | protein-coding |
Description | aconitase 2, mitochondrial |
Other Description | aconitate hydratase, mitochondrial|citrate hydro-lyase |
Swissprots | Q6FHX0 O75809 Q8TAQ6 Q99798 Q5JZ41 |
Accessions | AAC39921 AAD19351 EAW60435 EAW60436 Q99798 AA724140 AK293562 BAG57034 AK296260 BAG58973 AK297213 BAG59696 AK301321 BAG62870 AK302691 BAG63920 AK314845 BAG37362 BC014092 AAH14092 BC026196 AAH26196 CR456365 CAG30251 CR536568 CAG38805 CU012932 CAK54363 CU013220 CAK54662 DQ893674 ABM84600 DQ895836 ABM86762 U80040 AAB38416 NM_001098 NP_001089 |
Function | Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. {ECO:0000250}. |
Subcellular Location | Mitochondrion {ECO:0000250}. |
Top Pathways | Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, Carbon metabolism |
ACO2 CRISPR/Cas9 KO Plasmid (h) - sc-404434 from Santa Cruz Biotechnology
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ACO2 HDR Plasmid (h) - sc-404434-HDR from Santa Cruz Biotechnology
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ACO2 Double Nickase Plasmid (h) - sc-404434-NIC from Santa Cruz Biotechnology
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ACO2 Double Nickase Plasmid (h2) - sc-404434-NIC-2 from Santa Cruz Biotechnology
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ACO2 CRISPR Activation Plasmid (h) - sc-404434-ACT from Santa Cruz Biotechnology
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ACO2 CRISPR Activation Plasmid (h2) - sc-404434-ACT-2 from Santa Cruz Biotechnology
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ACO2 Lentiviral Activation Particles (h) - sc-404434-LAC from Santa Cruz Biotechnology
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ACO2 Lentiviral Activation Particles (h2) - sc-404434-LAC-2 from Santa Cruz Biotechnology
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ACO2 siRNA (h) - sc-61936 from Santa Cruz Biotechnology
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ACO2 shRNA Plasmid (h) - sc-61936-SH from Santa Cruz Biotechnology
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ACO2 shRNA (h) Lentiviral Particles - sc-61936-V from Santa Cruz Biotechnology
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Aconitase 2 RNAi - H00000050-R01 from Novus Biologicals
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MISSION® esiRNA - EHU147801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2723 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2723 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03081 from Sigma-Aldrich
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ACO2 siRNA (Human) - CRH0038 from Cohesion Biosciences
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ACO2 - MBS8205774 from MyBioSource
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Human ACO2 siRNA - orb260540 from Biorbyt
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ACO2 shRNA Plasmid (Human) - CHH0038 from Cohesion Biosciences
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