| Gene Symbol |
KCNE4
|
| Entrez Gene |
23704
|
| Alt Symbol |
MIRP3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, voltage gated subfamily E regulatory beta subunit 4
|
| Other Description |
MINK-related peptide 3|cardiac voltage-gated potassium channel accessory subunit 4|minimum potassium ion channel-related peptide 3|potassium channel subunit beta MiRP3|potassium voltage-gated channel subfamily E member 4|potassium voltage-gated channel, Isk-related family, member 4
|
| Swissprots |
Q8WWG9 Q96CC4 B7Z275 Q53SM4
|
| Accessions |
AAX93228 ABQ01241 EAW70810 Q8WWG9 AK294423 BAH11761 AK313203 BAG36019 AY065987 AAL49979 BC014429 AAH14429 BM662449 BP348485 BP359441 BP362695 DQ192293 ABB00306 DQ892516 ABM83442 EU176698 ABW03499 NM_080671 NP_542402
|
| Function |
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. May associate with KCNQ1/KVLTQ1 and inhibit potassium current.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Predominantly expressed in embryo and adult uterus. Low expression found in kidney, small intestine, lung and heart. {ECO:0000269|PubMed:12096056}.
|
![Western Blot: KCNE4 Overexpression Lysate (Adult Normal) [NBL1-12151] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KCNE4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8214_KCNE4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12151-img0002.jpg)