CNFN

Gene Symbol CNFN
Entrez Gene 84518
Alt Symbol PLAC8L2
Species Human
Gene Type protein-coding
Description cornifelin
Other Description cornefied envelope protein cornefilin
Swissprots Q9BYD5 B2R569
Accessions EAW57134 Q9BYD5 AB049591 BAB40656 AK312080 BAG35016 BC101197 AAI01198 BC101198 AAI01199 XM_005259332 XP_005259389 XM_011527396 XP_011525698 XM_011527397 XP_011525699 NM_032488 NP_115877
Function Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. {ECO:0000269|PubMed:15147942}.
Subcellular Location Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope. {ECO:0000250}.
Tissue Specificity Abundant in the cervix. Moderately abundant in the uterus and fetal skin. Expression is markedly increased in psoriatic skin (18.5 fold increase in comparison with normal skin) and its overexpression alters the protein composition of cornified cell envelope (CE), but does not affect keratinocyte differentiation. Expressed in the granular cell layer of epidermis in uninvolved psoriatic skin and in the psoriatic lesions it is found in the upper-spinous layer. Increased expression also seen in atopic dermatitis (14.3 fold increase in comparison with normal skin) and mycosis fungoides (4.6 fold increase in comparison with normal skin) and in both conditions expressed in the granular cell layer of epidermis. {ECO:0000269|PubMed:15147942}.

cornifelin (N-14) - sc-242501 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

cornifelin (T-17) - sc-242502 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CNFN antibody - ab151047 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human cervix tissue labeling CNFN with ab151047 at 1/200 dilution.

CNFN Antibody - NBP2-14668 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CNFN antibody produced in rabbit - HPA049073 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CNFN:<B>Cat. No. HPA049073</B>: Immunohistochemical staining of human cervix, uterine shows distinct membranous positivity in superficial layer of squamous epithelial cells.

Anti-CNFN (aa 1-56) polyclonal antibody - DPABH-03201 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

CNFN Antibody - NBP2-55563 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CNFN Antibody, Biotin conjugated - CSB-PA005641LD01HU from Cusabio

Host Rabbit
Clonality Polyclonal

CNFN Antibody, FITC conjugated - CSB-PA005641LC01HU from Cusabio

Host Rabbit
Clonality Polyclonal

CNFN Antibody, HRP conjugated - CSB-PA005641LB01HU from Cusabio

Host Rabbit
Clonality Polyclonal

CNFN Antibody - CSB-PA005641LA01HU from Cusabio

Host Rabbit
Clonality Polyclonal
<img /><p>IHC image of CSB-PA005641LA01HU diluted at 1:300 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized tissue using an HRP conjugated SP system.</p><p><a href="http://www.cusabio.cn/images/antibody/4/CSB-PA005641LA01HU-IF.jpg" target="_blank"> </a></p>
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