MIA3

Gene Symbol	MIA3
Entrez Gene	375056
Alt Symbol	ARNT, D320, TANGO, TANGO1, UNQ6077
Species	Human
Gene Type	protein-coding
Description	melanoma inhibitory activity family, member 3
Other Description	C219-reactive peptide|melanoma inhibitory activity protein 3|transport and Golgi organization protein 1
Swissprots	Q3S4X3 A8K2S0 Q92580 Q8N8M5 Q6UVY8 Q5JRB2 Q5JRA6 Q5JRA5 Q5JRB0 Q86Y60 A8MT13 Q14083 A8MT05 Q5JRB1 B7Z430
Accessions	CAH05393 EAW93267 Q5JRA6 AK025122 AK025506 AK026489 AK096526 BAC04810 AK290335 BAF83024 AK296712 BAH12416 AK307412 AX775845 CAE11622 AY359091 AAQ89449 BC031805 BC047116 AAH47116 BG429750 BP423646 CK724924 D87742 BAA13448 DA040423 DQ166034 AAZ95512 L34688 AAB00324 XM_005273121 XP_005273178 XM_006711304 XP_006711367 XM_011509513 XP_011507815 NM_001300867 NP_001287796 NM_198551 NP_940953
Function	Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. {ECO:0000269|PubMed:19269366}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:19269366}; Single-pass type I membrane protein {ECO:0000269|PubMed:19269366}. Note=Localizes at endoplasmic reticulum exit sites. After loading of COL7A1 into transport carriers, it is not incorporated into COPII carriers and remains in the endoplasmic reticulum membrane.
Tissue Specificity	Broadly expressed, except in bone marrow and peripheral blood mononuclear cells. Down-regulated in melanoma tissue. {ECO:0000269|PubMed:15183315, ECO:0000269|PubMed:17044017}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ARNT / HIF-1-Beta Antibody Blocking Peptide - LS-E10788 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARNT / HIF-1-Beta Antibody Blocking Peptide - LS-E10789 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ARNT/HIF-1 beta Protein - H00000405-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ARNT/HIF-1 beta Protein - H00000405-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Arnt Blocking Peptide - 33R-8649 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MIA3 fusion protein - ag11514 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MIA3 fusion protein - ag11638 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Melanoma inhibitory activity protein 3(MIA3) ,partial - CSB-YP711448HU CSB-EP711448HU CSB-BP711448HU CSB-MP711448HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MIA3 Recombinant Protein Antigen - NBP2-33770PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MIA3 Protein - NBP2-34160PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ARNT Peptide, Human - M34GP00963H from Creative Peptides Category Peptide Source Synthetic. Species Human

MIA3 Peptide, Human - M34GP09501H from Creative Peptides Category Peptide Source Synthetic. Species Human

Melanoma inhibitory activity protein 3 (MIA3), partial, Recombinant Protein - MBS1285085 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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